Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak. The EBOV genomic data are consistent with that tree. It confirms that there was a single source for the Nigerian infections, shows that the Nigerian EBOV lineage nests within a lineage previously seen in Liberia but is genetically distinct from it, and supports the conclusion that transmission from Nigeria to elsewhere did not occur.
Our findings show the highest LASV positivity in small rodents ever recorded and the first direct detection of LASV in
Tatera
spp. Our findings also indicate the abundance of LASV-infected small rodents in houses, with probable interspecies transmission through vertical and horizontal coitus routes.
This work was carried out in collaboration between the authors. Author FA designed the study, performed laboratory and statistical analyses, wrote the protocol and wrote the first draft of the manuscript. Author POA procured the cassava varieties and performed the proximate analysis in the laboratory. Authors KSA, YAA, TOA, SOF, NOO, UDA, TAK and GGD performed sample collection and laboratory analyses of the study. Author OF contributed to the development of protocol and provided technical support. All authors read and approved the final manuscript.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.