This pilot study compared the efficacy and safety of two simple dosing algorithms, one based on anti-Müllerian Hormone (AMH) and the other on the antral follicle count (AFC), to determine the starting dose of recombinant FSH (rFSH) for ovarian stimulation in 348 women. Patients were randomized to a predefined AMH- or AFC-based algorithm. The proportion of cycles with the desired response was similar when rFSH dose was determined using AMH or AFC (35.2% versus 28.4%). There was a significant difference between the groups in the proportion of cycles with a hyperresponse (8.6% and 17.4%, but the incidence of ovarian hyperstimulation syndrome was similar (1.1% and 4.6%). There were no significant differences between two groups in outcomes, including implantation (19.3% versus 19.0%), clinical pregnancy (38.0% versus 46.9%), multiple pregnancy (16.5% versus 15.2%) and miscarriage (7.0% versus 8.3%). However, statistically significant differences in ovarian response were evident among the AMH and AFC subgroups: for AMH, Desired and Hypo; for AFC, Hypo and Hyper. This pilot study provides information for developing protocols to further validate the use of either AMH or AFC to guide the starting dose of rFSH in ovarian stimulation. The ideal outcome for couples undergoing IVF treatment is the birth of a healthy baby. One factor that might influence this is retrieving an adequate number of eggs, which are obtained using various treatment protocols. A group of drugs called gonadotrophins have been used for more than 20years to stimulate the ovaries to produce eggs. However, the dose to start treatment has not been clearly defined. A few studies have looked at ways to use the best gonadotrophin dose for each woman, but to be useful in the clinic any approach needs to be simple and easy to use. This study compared the effectiveness and safety of two simple approaches to determining the starting dose of recombinant FSH (rFSH) for ovarian stimulation in women undergoing IVF. One was based on the concentration of a hormone secreted by developing eggs (anti-Müllerian hormone; AMH) and the other on the number of developing follicles (antral follicle count; AFC). The number of cycles achieving the desired response in terms of number of eggs was similar when rFSH dose was guided using AMH or AFC, and the incidence of ovarian hyperstimulation syndrome was also similar. In addition, rates of clinical pregnancy, multiple pregnancy and miscarriage did not differ between the two groups. However, patients with low AMH concentrations or low AFC had a poor response to ovarian stimulation. This pilot study provides useful information from which new studies can further assess these approaches to personalizing treatment during IVF.

Monitoring surface water provides vital information in water management; however, limited data is a fundamental challenge for most developing countries, such as Vietnam. Based on advanced remote sensing technologies, the authors proposed a methodology to process satellite images and use their outcomes to extract surface water in water resource management of Quang Nam province. Results of the proposed study show good agreement with in situ measurement data when the obtained Overall Accuracy and Kappa Coefficient were greater than 90% and 0.99, respectively. Three potential applications based on the surface water results are selected to discuss sustainable water management in Quang Nam province. Firstly, reservoir operating processes can be examined, enhanced, and even developed through long-term extracted water levels, which are the interpolation results between the extracted surface water area and the water level–area–volume curve. Secondly, the long-term morphological change for the Truong Giang river case between 1990 and 2019 can also be detected from the Water Frequency Index performance and provided additional information regarding permanent and seasonal water changes. Lastly, the flood inundation extent was extracted and separated from permanent water to assess the damage of the Mirinae typhoon on 2 November 2009 in terms of population and crop aspects.

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Sau đây chúng tôi sẽ trình bày về tình hình thương mại điện tử trong dịch bệnh và thực tế sự phát triển của các sàn thương mại điện tử tại Việt Nam nhằm thảo luận để phân tích, đánh giá và có góc nhìn rộng hơn đối với sự phát triển của thương mại điện tử.