Background: Although dyslipidemia is a well-established risk factor for coronary artery disease, its relationship to ischemic cerebrovascular disease has remained unclear, perhaps because of the heterogeneous nature of stroke. Recent studies indicate postprandial triglyceride (TG) had a better association with cardiovascular events and metabolic syndrome than fasting TG.Aim & Objective of the study: The aim of this study is to investigate if serum TG levels predict stroke severity on admission with correlation of fasting and post-prandial serum TG levels Methods: 80 patients of acute ischemic stroke who were admitted to Bhaskar Medical College within 24 hours of development of symptoms were included in this study in which fasting TG levels & post prandial TG levels were done. Stroke severity on admission was assessed using Scandinavian Stroke Scale (SSS). The patients were divided into 2 groups: those with severe stroke (SSS ≤25) and those with mild/moderate stroke (SSS >25). Results: Of the 80 patients studied, 54 were males and 26 were females. Among the males, 42 had FTG≤2.3mmol/l and 12 had FTG levels >2.3mmol/l & 27 had PPTG≤2.3mmol/l and 27 had PPTG levels >2.3mmol/l. Of the 26 females 18 had FTG≤2.3mmol/l and 8 patients had FTG levels >2.3mmol/l & 15 had PPTG≤2.3mmol/l and 11 had PPTG levels >2.3mmol/l. In this study the number of patients with severe stroke (SSS≤25) were 20 of which 15 had F TG≤2.3mmol/l and only 5 patient had F TG>2.3mmol/l & 9 had PPTG≤2.3mmol/l and 12 had PPTG>2.3mmol/l. Out of 80 patients, 44 were hypertensive and 32 had FTG≤2.3mmol/l and 12 had FTG>2.3mmol/l & 19 had PPTG≤2.3mmol/l and 25 had PPTG>2.3mmol/l of the remaining 36 non hypertensive patients, 30 had FTG≤2.3mmol/l and 6 had FTG>2.3mmol/l & 25 had PPTG≤2.3mmol/l and 11 had PPTG>2.3mmol/l. 16 were IHD patients of which 12 had FTG≤2.3mmol/l and 4 had FTG>2.3mmol/l & 8 had PPTG≤2.3mmol/l and 8 had PPTG>2.3mmol/l & of the remaining 64 patients, 50 had FTG≤2.3mmol/l and 14 had FTG>2.3mmol/l & 30 had PPTG≤2.3mmol/l and 34 had PPTG>2.3mmol/l. The levels of serum FTG were not influenced by hypertension, IHD, age and sex of an individual but the level of serum PPTG were influenced by HTN. Conclusion: 1 In this study, mean serum fasting & post prandial serum triglyceride levels were not significantly associated with the severity of the stroke. As per this study hypertension, IHD, age and sex of an individual do not influence levels of serum fasting triglyceride levels but the serum post prandial triglyceride level were influenced by HTN.
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