Compounds. -This three-component, one-pot reaction between quinolones (Ia)-(Ic) or coumarin (Id), aldehydes (II), and indoles (III) provides access to antibacterial agents (IV) possessing excellent in vitro activities against S. aureus and E. faecium including methicillin-resistant S. aureus and vancomycin-resistant enterococci. -(YAMAMOTO*, Y.; KURAZONO, M.; Bioorg.
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