The application of coordination chemistry in the light of nanotechnology is a rapidly developing research field in medicine. Bismuth complexes have been widely and willingly used in biomedicine with satisfactory therapeutic effects, mostly in Helicobacter pylori eradication, but also as potential anti-microbial and anti-leishmanial agents. Additionally, in recent years, an application of bismuth-based compounds as potent anticancer drugs has also been studied extensively. Therefore, in this review, we want to highlight a number current problems connected with: (1) characterization of bismuth complexes based on thiosemicarbazone, hydrazone, and dithiocarbamate classes of ligands as potential chemotherapeutics, (2) pioneering research on application of bismuth-based nanoparticles and nanodots for radiosensitization, and (3) research challenges in using bismuth radionuclides in targeted radioimmunotherapy.
To evaluate the impact of the flexible positional isomeric ligands thiophene-2-acetate (2tpacCOO) and thiophene-3-acetate (3tpacCOO) on the construction and self-assembly process of Pb(II) polymers, two novel compounds, [Pb(2tpacCOO)2(H2O)]n (1) and...
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