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Classical orthogonal polynomials in one variable can be characterized as the only orthogonal polynomials satisfying a Rodrigues formula. In this paper, using the second kind Kronecker power of a matrix, a Rodrigues formula is introduced for classical orthogonal polynomials in two variables.

Differential properties for orthogonal polynomials in several variables are studied. We consider multivariate orthogonal polynomials whose gradients satisfy some quasi-orthogonality conditions. We obtain several characterizations for these polynomials including the analogues of the semiclassical Pearson differential equation, the structure relation and a differential-difference equation.