The Laser Interferometer Gravitational Wave Observatory (LIGO) consists of two widely separated 4 km laser interferometers designed to detect gravitational waves from distant astrophysical sources in the frequency range from 10 Hz to 10 kHz. The first observation run of the Advanced LIGO detectors started in September 2015 and ended in January 2016. A strain sensitivity of better than 10 −23 / √ Hz was achieved around 100 Hz. Understanding both the fundamental and the technical noise sources was critical for increasing the astrophsyical strain sensitivity. The average distance at which coalescing binary black hole systems with individual masses of 30 M could be detected above a signal-to-noise ratio (SNR) of 8 was 1.3 Gpc, and the range for binary neutron star inspirals was about 75 Mpc. With respect to the initial detectors, the observable volume of the Universe increased by a factor 69 and 43, respectively. These improvements helped Advanced LIGO to detect the gravitational wave signal from the binary black hole coalescence, known as GW150914.

Electron–positron pair plasmas represent a unique state of matter, whereby there exists an intrinsic and complete symmetry between negatively charged (matter) and positively charged (antimatter) particles. These plasmas play a fundamental role in the dynamics of ultra-massive astrophysical objects and are believed to be associated with the emission of ultra-bright gamma-ray bursts. Despite extensive theoretical modelling, our knowledge of this state of matter is still speculative, owing to the extreme difficulty in recreating neutral matter–antimatter plasmas in the laboratory. Here we show that, by using a compact laser-driven setup, ion-free electron–positron plasmas with unique characteristics can be produced. Their charge neutrality (same amount of matter and antimatter), high-density and small divergence finally open up the possibility of studying electron–positron plasmas in controlled laboratory experiments.

The new generation of gravitational waves detectors require unprecedented levels of isolation from seismic noise. This article reviews the seismic isolation strategy and instrumentation developed for the Advanced LIGO observatories. It summarizes over a decade of research on active inertial isolation and shows the performance recently achieved at the Advanced LIGO observatories. The paper emphasizes the scientific and technical challenges of this endeavor and how they have been addressed. An overview of the isolation strategy is given. It combines multiple layers of passive and active inertial isolation to provide suitable rejection of seismic noise at all frequencies. A detailed presentation of the three active platforms that have been developed is given. They are the hydraulic pre-isolator, the single stage internal isolator and the two-stage internal isolator. The architecture, instrumentation, control scheme and isolation results are presented for each of the three systems. Results show that the seismic isolation sub-system meets Advanced LIGO stringent requirements and robustly supports the operation of the two detectors.

The generation of ultra-relativistic positron beams with short duration (τ e + ≤ 30 fs), small divergence (θ e + 3 mrad), and high density (n e + 10 14 − 10 15 cm −3 ) from a fully optical setup is reported. The detected positron beam propagates with a high-density electron beam and γ-rays of similar spectral shape and peak energy, thus closely resembling the structure of an astrophysical leptonic jet. It is envisaged that this experimental evidence, besides the intrinsic relevance to laserdriven particle acceleration, may open the pathway for the small-scale study of astrophysical leptonic jets in the laboratory.Creating and characterizing high-density beams of relativistic positrons in the laboratory is of paramount importance in experimental physics, due to their direct application to a wide range of physical subjects, including nuclear physics, particle physics, and laboratory astrophysics. Arguably, the most practical way to generate them is to exploit the electromagnetic cascade initiated by the propagation of an ultra-relativistic electron beam through a high-Z solid. This process is exploited to generate low-energy positrons in injector systems for conventional accelerators such as the Electron-Positron Collider (LEP) [1]. In this case, an ultra-relativistic electron beam (E e − ≈ 200 MeV) was pre-accelerated by a LINAC and then directed onto a tungsten target. The resulting positron population, after due accumulation in a storage ring, was further accelerated by a conventional, large-scale (R ≈ 27 km), synchrotron accelerator up to a peak energy of 209 GeV. The large cost and size of these machines have motivated the study of alternative particle accelerator schemes. A particularly compact and promising system is represented by plasma devices which can support much higher accelerating fields (of the order of 100s of GV/m, compared to MV/m in solid-state accelerators) and thus significantly shorten the overall size of the accelerator. Laser-driven generation of electron beams with energies per particle reaching [2][3][4][5], and exceeding [6], 1 GeV have been experimentally demonstrated and the production of electron beams with energies approaching 100 GeV is envisaged for the next generation of highpower lasers (1 -10 PW) [7]. Hybrid schemes have also been proposed and successfully tested in first proof-ofprinciple experiments [8,9]. On the other hand, laserdriven low energy positrons (E e + ≈ 1−5 MeV) have been first experimentally obtained by C. Gahn and coworkers [10] and recently generated during the interaction of a picosecond, kiloJoule class laser with thick gold targets [11][12][13][14]. Despite the intrinsic interest of these results, the low energy and broad divergence reported (E e + ≤ 20 MeV and θ e + ≥ 350 mrad , respectively) still represent clear limitations for future use in hybrid machines.The possibility of generating high density and high energy electron-positron beams is of central importance also for astrophysics, due to their similarity to jets of long gamma-ray bursts (GRBs), whic...

The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701).

New generations of gravity wave detectors require unprecedented levels of vibration isolation. This paper presents the final design of the vibration isolation and positioning platform used in Advanced LIGO to support the interferometer's core optics. This five-ton two-and-half-meter wide system operates in ultra-high vacuum.It features two stages of isolation mounted in series. The stages are imbricated to reduce the overall height. Each stage provides isolation in all directions of translation and rotation. The system is instrumented with a unique combination of low noise relative and inertial sensors. The active control provides isolation from 0

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Extreme ultraviolet (EUV) lithography is expected to succeed in 193-nm immersion multi-patterning technology for sub-10-nm critical layer patterning. In order to be successful, EUV lithography has to demonstrate that it can satisfy the industry requirements in the following critical areas: power, dose stability, etendue, spectral content, and lifetime. Currently, development of second-generation laser-produced plasma (LPP) light sources for the ASML’s NXE:3300B EUV scanner is complete, and first units are installed and operational at chipmaker customers. We describe different aspects and performance characteristics of the sources, dose stability results, power scaling, and availability data for EUV sources and also report new development results.