Precise reaction cross sections (oR) for 24_38M g on C targets at energies around 240 M eV /nucleon have been measured at the Radioactive Isotope Beam Factory at RIKEN. The oR for 36-38 Mg have been measured for the first time. An enhancement o f oR compared to the systematics for spherical stable nuclei has been observed, especially in the neutron-rich region, which reflects the deformation of those isotopes. In the vicinity of the drip line the aR for 37Mg is especially large. It is shown by analysis using a recently developed theoretical method that this prominent enhancement of oR for 37Mg should come from the p-orbital halo formation breaking the N = 28 shell gap.Since the early years of the study of atomic nuclei, the nuclear shell model has been the basic framework for understanding nuclear structure. The high stability of nuclei with certain numbers of neutrons (or protons) observed in stable nuclei indicates the existence of the shells filled at certain so-called "magic numbers." Studies in the last few decades have revealed that those magic numbers are sometimes broken or changed in unstable nuclei [1], The breakdown of the N = 20 shell gap between the sd and f p shells has been extensively studied since the irregularities in binding energies and 2+ excitation energies were observed in neutron-rich nuclei around N = 20 [2-6]. The term "island of inversion" was applied to this region [6] and deformed nuclear structures related to the changing of shell structures have been reported in this region [7]. The vanishing of the N = 28 shell closure has been also extensively studied, starting from neutronrich S-Ar isotopes [8][9][10][11][12][13][14]. The development of deformation observed in those nuclei could be interpreted as degeneracy of the f p shell, which induces strong quadrupole deformation [9][10][11][13][14][15][16][17][18]. Such deformation has been reported also for Si isotopes [19,20], and studies have recently indicated that this * takechi @ np.gs .niigata-u. ac .jp PACS number(s): 21.10.Gv, 25.60.Dz phenomenon could be seen even in a very neutron-rich Mg region [21].The purpose of our present study is to elucidate the changes of nuclear structures, such as a development of deformation, a breakdown of the magic numbers and possible halo formation in Mg isotopes, from the stability line to the vicinity of the neutron drip line. For this purpose, precise measurements of reaction cross sections for 24_38Mg have been performed at the Radioactive Isotope Beam Factory (RIBF) at RIKEN. The reaction cross section aR or interaction cross section ay reflects the nuclear size, and has been a powerful probe in searching for halo formation since the first study by Tanihata et al. [22], Recently, measurements of o, for Ne isotopes performed at RIBF [23] have successfully revealed the halo structure of 3lNe in which the sd-pf shell inversion associated with nuclear deformation causes the formation of a halo [23][24][25]. Moreover, theoretical studies on those data have shown that a precise data set on crR is v...
This study aimed to evaluate the performance of the hybrid deformable image registration (DIR) method in comparison with intensity-based DIR for pelvic cone-beam computed tomography (CBCT) images, using intensity and anatomical information. Ten prostate cancer patients treated with intensity-modulated radiation therapy (IMRT) were studied. Nine or ten CBCT scans were performed for each patient. First, rigid registration was performed between the planning CT and all CBCT images using gold fiducial markers, and then DIR was performed. The Dice similarity coefficient (DSC) and center of mass (COM) displacement were used to evaluate the quantitative DIR accuracy. The average DSCs for intensity-based DIR for the prostate, rectum, bladder, and seminal vesicles were 0.84 ± 0.05, 0.75 ± 0.05, 0.69 ± 0.07 and 0.65 ± 0.11, respectively, whereas those values for hybrid DIR were 0.98 ± 0.00, 0.97 ± 0.01, 0.98 ± 0.00 and 0.94 ± 0.03, respectively (P < 0.05). The average COM displacements for intensity-based DIR for the prostate, rectum, bladder, and seminal vesicles were 2.0 ± 1.5, 3.7 ± 1.4, 7.8 ± 2.2 and 3.6 ± 1.2 mm, whereas those values for hybrid DIR were 0.1 ± 0.0, 0.3 ± 0.2, 0.2 ± 0.1 and 0.6 ± 0.6 mm, respectively (P < 0.05). These results showed that the DSC for hybrid DIR had a higher DSC value and smaller COM displacement for all structures and all patients, compared with intensity-based DIR. Thus, the accumulative dose based on hybrid DIR might be trusted as a high-precision dose estimation method that takes into account organ movement during treatment radiotherapy.
Our developed phantom enabled the evaluation of spatial DIR accuracy for the female pelvic region for the first time. Although the DSCs are high, the spatial errors can still be significant and our developed phantom facilitates their quantification. Our results showed that optimization is needed to identify suitable DIR settings. For determining suitable DIR settings, our method of evaluating spatial DIR accuracy using the 3D-printed phantom may prove helpful.
The purpose of this study was to evaluate the accuracy of commercially available software, using patient DVH‐based QA metrics, by investigating the correlation between estimated 3D patient dose and magnitude of MLC misalignments. We tested 3DVH software with an ArcCHECK. Two different calculating modes of ArcCHECK Planned Dose Perturbation (ACPDP) were used: “Normal Sensitivity” and “High Sensitivity”. Ten prostate cancer patients treated with hypofractionated VMAT (67.6 Gy/26 Fr) in our hospital were studied. For the baseline plan, we induced MLC errors (−0.75,−0.5,−0.25,0.25,0.5, and 0.75 mm for each single bank). We calculated the dose differences between the ACPDP dose with error and TPS dose with error using gamma passing rates and using DVH‐based QA metrics. The correlations between dose estimation error and MLC position error varied with each structure and metric. A comparison using 1normal%/1 mm gamma index showed that the larger was the MLC error‐induced, the worse were the gamma passing rates. Slopes of linear fit to dose estimation error versus MLC position error for mean dose and D95 to the PTV were 1.76 and 1.40normal% mm−1, respectively, for “Normal Sensitivity”, and −0.53 and 0.88normal% mm−1, respectively, for “High Sensitivity”, showing better accuracy for “High Sensitivity” than “Normal Sensitivity”. On the other hand, the slopes for mean dose to the rectum and bladder, V35 to the rectum and bladder and V55 to the rectum and bladder, were −1.00,−0.55,−2.56,−1.25,−3.53, and 1.85normal% mm−1, respectively, for “Normal Sensitivity”, and −2.89,−2.39,−4.54,−3.12,−6.24, and −4.11normal% mm−1, respectively, for “High Sensitivity”, showing significant better accuracy for “Normal Sensitivity” than “High Sensitivity”. Our results showed that 3DVH had some residual error for both sensitivities. Furthermore, we found that “Normal Sensitivity” might have better accuracy for the DVH metric for the PTV and that “High Sensitivity” might have better accuracy for DVH metrics for the rectum and bladder. We must be willing to tolerate this residual error in clinical care.PACS number: 87.55Qr
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