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(Abstracted from Ultrasound Obstet Gynecol 2017;50:228–235)
There is substantial evidence that chronic hypertension (CH) is associated with adverse pregnancy outcomes. Although meta-analyses of studies examining this issue have been previously conducted, confounding factors and heterogeneity between included studies weaken their impact.
(Abstracted from Ultrasound Obstet Gynecol 2019;53(2):208–213)
In singleton pregnancies, screening for the major trisomies using a combination of fetal nuchal translucency (NT) thickness, serum β-human chorionic gonadotropin, and pregnancy-associated plasma protein A can detect approximately 90% of cases of trisomy 13, 18, or 21, at a false-positive rate of 5%. In twin pregnancies, use of the combined test can achieve a similar detection rate (DR) for trisomy 21, but with a higher false-positive rate of about 6%.
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