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Project MAT2017-85999-P MINECO/AEI/FEDER/UE supported by the Ministry of Economy and Competitiveness and European Regional Development Fund. The authors thank the technical support of Álvaro Carrasco-Carmona for the manuscript edition.

Self-etching primers and phosphoric acid promote similar water wettability increase. However, self-etching primers provided lower dentin roughness increase than pretreatment with phosphoric acid. The presence of smear layer did not affect the results of self-etching and phosphoric acid treatments.