Our results demonstrate the existence of an endometrial microbiota that is highly stable during the acquisition of endometrial receptivity. However, pathological modification of its profile is associated with poor reproductive outcomes for in vitro fertilization patients. This finding adds a novel microbiological dimension to the reproductive process.

(Abstracted from Am J Obstet Gynecol 2016;215(6):684–703) In 2002, the vaginal microbiota was first identified using molecular methods that allowed detection of nonculturable bacteria. Alterations in vaginal microbiota could have clinical implications for reproductive and obstetric processes.