This study empirically investigates the complex interplay between the severity of the coronavirus pandemic, mobility changes in retail and recreation, transit stations, workplaces, and residential areas, and lockdown measures in 88 countries around the world during the early phase of the pandemic. To conduct the study, data on mobility patterns, socioeconomic and demographic characteristics of people, lockdown measures, and coronavirus pandemic were collected from multiple sources (e.g., Google, UNDP, UN, BBC, Oxford University, Worldometer). A Structural Equation Modeling (SEM) framework is used to investigate the direct and indirect effects of independent variables on dependent variables considering the intervening effects of mediators. Results show that lockdown measures have significant effects to encourage people to maintain social distancing so as to reduce the risk of infection. However, pandemic severity and socioeconomic and institutional factors have limited effects to sustain social distancing practice. The results also explain that socioeconomic and institutional factors of urbanity and modernity have significant effects on pandemic severity. Countries with a higher number of elderly people, employment in the service sector, and higher globalization trend are the worst victims of the coronavirus pandemic (e.g., USA, UK, Italy, and Spain). Social distancing measures are reasonably effective at tempering the severity of the pandemic.

On the premise that knowledge creation defines contemporary metropolitan regions, we profile them by their inventive networks, as measured by a variety of complementary social network, technology, and patenting metrics that distinguish scalar and structural aspects. Using a comprehensive, multiyear database of patent applications, we investigate whether the knowledge creation network profiles are discriminating characteristics of metropolitan regions by establishing a new urban taxonomy for metropolitan areas in the United States. The four-class taxonomy is not only statistically significant, but it is also economically meaningful in terms of economic performance of metropolitan areas. We find that metropolitan areas benefit from a higher density of inventors in the population, and that there is a positive correlation between economic performance and metropolitan areas with inventor teams working in similar or complementary areas of technology. In fact, the structure of knowledge creation networks are fundamental to economic performance and extends to metropolitan growth rates in jobs and income.

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Prediction of complex epidemiological systems such as COVID-19 is challenging on many grounds. Commonly used compartmental models struggle to handle an epidemiological process that evolves rapidly and is spatially heterogeneous. On the other hand, machine learning methods are limited at the beginning of the pandemics due to small data size for training. We propose a deep learning approach to predict future COVID-19 infection cases and deaths 1 to 4 weeks ahead at the fine granularity of US counties. The multi-variate Long Short-term Memory (LSTM) recurrent neural network is trained on multiple time series samples at the same time, including a mobility series. Results show that adding mobility as a variable and using multiple samples to train the network improve predictive performance both in terms of bias and of variance of the forecasts. We also show that the predicted results have similar accuracy and spatial patterns with a standard ensemble model used as benchmark. The model is attractive in many respects, including the fine geographic granularity of predictions and great predictive performance several weeks ahead. Furthermore, data requirement and computational intensity are reduced by substituting a single model to multiple models folded in an ensemble model.