The absence of a trench and the existence of a separate, western chain of islands in the central New Hebrides island arc are a consequence of earlier tectonic evolution, and not the result of subduction of the d'Entrecusteaux Zone as was previously suggested. Because of tectonic consolidation in the western islands prior to present subduction, a resistant block was created opposing subduction, and a trench nevcr did form here. The d'Entrecasteaux Zone is responsible only locally for additional deformation of the subducting plate, in a way that can be regarded as an initial stage of obduction.
It was previously assumed that a new genetic method in yeast, termed gene-gene interference, leads to the selection of genes that antagonize, and/or are antagonized by, the particular reference gene used for their selection (Daniel 1993). In this paper two pieces of evidence are advanced in favour of this view. Firstly, the reconstitution of a system of known antagonistic genes was shown to be detectable by the gene-gene interference method. Secondly, since ART1, a new gene selected in reference to the protein kinase A gene, has been shown to contain in its deduced polypeptide a putative site for phosphorylation by protein kinase A, a mutagenesis study directed toward this putative site has been performed. Two phenotypes-in vivo filamenting activity and gene-gene interference relative to the protein kinase A gene-were tested with the various mutations thus obtained and found to be consistent with the hypothesis that, under physiological conditions, phosphorylation by protein kinase A exerts an inhibitory effect on Art1 activity. The relevance of these findings on the mechanisms and potential applications of the gene-gene interference phenomenon is discussed.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.