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Almost two-thirds of the patients reached full consciousness. LOC at admission, aetiology and interval since injury were found to be significant prognostic factors. Traumatic patients had a much better outcome than non-traumatic patients. A comparison with earlier outcome studies showed a more favourable outcome than expected. It is argued that a multi-centre study is needed to confirm possible effects of EINP.

The results are in line with findings concerning distress in caregivers of patients suffering from personality disorders in general, posttraumatic stress disorder or schizophrenia. The mechanism behind the increased levels of distress in our sample is not clear, however. Either exposure to the problematic behaviour of the patient, selective mating or a combination of both might have been responsible for the effect.

More patients with TBI than expected reached a (semi-) independent level of functioning, indicating a possible effect of EINP. Patients suffering from nTBI did not demonstrate these outcome levels. Only a few patients stayed in a vegetative state for more than a couple of years. In this cohort of severe brain-injured young people, the DRS offered the best investigative possibilities for long-term level of functioning.

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