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Guillain-Barré syndrome (GBS) is the most common acute paralytic neuropathy, characterized by symmetrical weakness of the limbs and hyporeflexia or areflexia. GBS usually occurs after an infection, with two-thirds of GBS patients having a history of respiratory or gastrointestinal infection before GBS onset. 1 During the progressive phase, 20%-30% of patients need mechanical ventilation (MV) in an intensive care unit (ICU) because of respiratory failure, which can worsen functional outcomes and even lead to death. 2-4 Therefore, it is very important to find early predictors of MV in patients with GBS.