Bone marrow mesenchymal stem cells (MSCs) have improved cardiac performance when administered after acute myocardial infarction (MI) in both large-animal models and in patients.1,2 However, the results from randomized controlled clinical trials have been less impressive; the authors of one meta-analysis concluded that left ventricular ejection fractions (LVEFs) increased by just 2.92% in response to cell therapy.
FDG-PET is a promising tool to assess the chemotherapy response of osteosarcoma noninvasively. The TBR was better than SUV max in evaluating the chemotherapy response in this study.
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