A case of hyperkeratosis lenticularis perstans (Flegel's disease) was studied histopathologically comparing early and old lesions. The age of the lesions were judged by both the patient's history and direct observation. The histopathologic and immunophenotypic features of a new lesion were essentially in accordance with previous findings. However, the old lesion had obviously different pathologic features. These included the absence of epidermal atrophy and infiltrate in the upper dermis under the lesion. Ultrastructural studies revealed that the presence of many normal-appearing membrane-coating granules in the keratinocytes of the old lesion, whereas the organelles were not found in the keratinocytes of the early lesion.
The growth process of 2223 phase in a leaded Bi-Sr-Ca-Cu oxide system has been investigated under various oxygen partial pressures using differential thermal analysis, combined with XRD of the quenched specimen. It is shown that under a slow heating rate, the DTA curves exhibit two or three endothermic peaks between 820 to 900°C, and the peak positions are lowered with reduction in the O2 partial pressure. The 2223 phase is found to grow most efficiently in the partial melting state sandwiched between the two endothermic peaks, and the temperature range between the two peaks becomes maximum around 0.1-atm O2 partial pressure.
The oxygen potential of thin films consisting of monophasic (Bi, Pb)2Sr2Ca2Cu3O
y
was controlled by annealing them under various oxygen partial pressures. The T
c of (Bi, Pb)2Sr2Ca2Cu3O
y
was found to decrease monotonously with decreasing oxygen potential. However, T
c did not change when annealed under higher oxygen pressure up to 2.9×104 torr. The carrier concentration was found to change with oxygen partial pressure, implying that oxygen supplies the carrier. An optimum range of the carrier concentration exists for attaining the highest T
c. This finding is consistent with those of other high T
c hole-type superconductors.
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