IMPORTANCE Depression has been associated with poorer medical outcomes in acute coronary syndrome (ACS), but there are few data on the effects of antidepressant treatment on long-term prognosis. OBJECTIVE To investigate the effect on long-term major adverse cardiac events (MACE) of escitalopram treatment of depression in patients with recent ACS.

Background To investigate the impacts of depression screening, diagnosis and treatment on major adverse cardiac events (MACEs) in acute coronary syndrome (ACS). Methods Prospective cohort study including a nested 24-week randomised clinical trial for treating depression was performed with 5–12 years after the index ACS. A total of 1152 patients recently hospitalised with ACS were recruited from 2006 to 2012, and were divided by depression screening and diagnosis at baseline and 24-week treatment allocation into five groups: 651 screening negative (N), 55 screening positive but no depressive disorder (S), 149 depressive disorder randomised to escitalopram (E), 151 depressive disorder randomised to placebo (P) and 146 depressive disorder receiving medical treatment only (M). Results Cumulative MACE incidences over a median 8.4-year follow-up period were 29.6% in N, 43.6% in S, 40.9% in E, 53.6% in P and 59.6% in M. Compared to N, screening positive was associated with higher incidence of MACE [adjusted hazards ratio 2.15 (95% confidence interval 1.63–2.83)]. No differences were found between screening positive with and without a formal depressive disorder diagnosis. Of those screening positive, E was associated with a lower incidence of MACE than P and M. M had the worst outcomes even compared to P, despite significantly milder depressive symptoms at baseline. Conclusions Routine depression screening in patients with recent ACS and subsequent appropriate treatment of depression could improve long-term cardiac outcomes.

Aim In many Asian countries, youth mental health services are not well‐developed and access to treatment is generally delayed. Here, we present a community‐based service model based on our experience with Mindlink, the first early‐intervention centre of its kind in Korea. Methods We describe the history of this mental health early‐intervention service and the characteristics of users, as well as its intervention programmes and research directions. We also propose ways to further develop youth mental health services. Results A community‐based early‐intervention service for youth was first introduced in 2012, when a special team was formed in a community mental health centre of Korea. As the numbers of young clients increased, a youth‐friendly, early‐intervention centre called Mindlink was opened in 2016. Mindlink targets those aged 15–30 years with mental illness less than 5 years in duration. Its goal is to detect mental illness in young people early and provide comprehensive multidisciplinary interventions. It provides intensive case management and group programmes including cognitive‐behavioural therapy, family intervention, psychoeducation, behavioural activation and physical health promotion. The Korean government has officially announced that the Mindlink model is effective and is currently in the process of scaling it up on a national level. Conclusion An accessible, youth‐friendly, stigma‐free, community mental health centre such as Mindlink allows early detection and appropriate management of mental illness in young patients.

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AC loss is one of the major topics in large AC power applications using high temperature superconductor such as power transformers, transmission cables and fault current limiters because it is closely related to operation efficiency. Multi-stacked tape conductors should be used to transport the large current in those power applications. A research of various arrangements of HTS tapes for multi-stacked tapes has been performed to increase the capacity of transport current in HTS power applications. In this paper, we studied magnetization loss and shield effect from several different arrangements of BSCCO tapes such as Face-to-Face type, regular matrix type (m 2) and irregular matrix type. The results show that the magnetization loss of the Face-to-Face arrangement was lower than those of the other matrix types for the same stacking numbers. We think that the result was due to the shield effect by demagnetization of adjacent HTS tapes which were located as face to face.