Structures of new antibiotics,mureidomycins (MRD's) A~D, were deduced from spectroscopic analyses and degradation studies. Tworesidues of m-tyrosine, one residue of 2-amino-3-iV-methylaminobutyric acid (AMBA) and methionine are present in all components of the complex. Uracil is contained in MRD's A and C, while dihydrouracil in MRD's B and D. Methionine and m-tyrosine are connected through an ureido bond, and uracil or dihydrouracil is linked to AMBA via enamine sugar moiety. In addition, MRD's C and D contain a glycine residue at the iV-terminal.
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