Background: A lot of women seek to get beautified. Consequently, some of the women often resort to using the products contained corticosteroids (CS) and other kinds of cosmetics, and this significantly increased with year 2018, due to the influence of social media. Despite the benefits, that excessive use of corticosteroids leads to serious side effects.Methods: 769 electronic questionnaires were completed by women for using corticosteroids in Hail, Saudi Arabia. Statistical comparison was done using SPSS (ANOVA test) was used to compare the answers given by the participants and P values less than 0.05 were considered significant.Results: 769 women responded. More than 30.3% of the patients were in the age group 31 to 40 years. The main reason for using the topical corticosteroids was to lighten skin color and reduce wrinkles.Conclusions: Misuse of topical corticosteroids is widely spread among women in Hail city, and this due to various reasons, the most important of which is to get bleaching and get rid of skin blemishes.

Background: Metformin is a drug used to treat patients with type 2 diabetes, especially those who suffer from obesity. It is also used in the treatment of women with polycystic ovary syndrome (PCOS). This disease is related to insulin resistance and multiplied blood sugar ranges. Furthermore, it has been established that the use of metformin improves the menstrual cycles and ovulation rates of these women. Methods: A structured questionnaire was conducted to determine the prevalence of breast cancer among women using metformin in the Ha’il region. Result: The incidence of breast cancer among women using metformin in the Ha’il region is very low. Thus, it can be said that breast cancer cases declined among diabetics taking metformin. This means that metformin use is associated with a lower risk of breast cancer in women with type 2 diabetes, even in cases where these women have a family history of breast cancer. Conclusions: According to previous findings, metformin has been linked to lower breast cancer risk in women with type 2 diabetes. Furthermore, the findings of this study corroborate the literature on this subject by indicating that there is a substantial connection between metformin use and a lower risk of breast cancer in women with type 2 diabetes. However, further in vitro and in vivo experiments are crucial to investigate the protective effect of metformin against breast cancer and to confirm our findings.

Nocturnal enuresis is defined as nighttime bedwetting in children five years of age or older in the absence of neurological or structural problems affecting the bladder. A wide variety of interventions are used to treat nocturnal enuresis include simple behavioral intervention, enuresis alarm, and pharmacological treatment—the aim of the study to assess the management of nocturnal enuresis in children. A prospective cross-sectional study included 150 children attend the advanced diagnostic center. Data collected by direct interview questionnaire was tested –coded and analyzed by SPSS version 20 in tables and graph &excel. The result of this study showed that the highest treatment adopted was simple-cognitive behavioral therapy (87%), with the highest (94.7%) of patient surveyed adopted lifting and awaking technique,(38%) of patient surveyed have taken imipramine, (26%) of patient surveyed have taken 75mg dose of imipramine, (37%)of patients surveyed had a full response from imipramine therapy. The study showed that the first-line treatment that is needed is simple-cognitive behavioral therapy with instruction regarding diet and fluids, and it is very useful. The main drug was used in the treatment of nocturnal enuresis is imipramine with a dose of 75mg.

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