Precise near-ground trajectory control is difficult for multi-rotor drones, due to the complex aerodynamic effects caused by interactions between multi-rotor airflow and the environment. Conventional control methods often fail to properly account for these complex effects and fall short in accomplishing smooth landing. In this paper, we present a novel deeplearning-based robust nonlinear controller (Neural-Lander) that improves control performance of a quadrotor during landing. Our approach combines a nominal dynamics model with a Deep Neural Network (DNN) that learns high-order interactions. We apply spectral normalization (SN) to constrain the Lipschitz constant of the DNN. Leveraging this Lipschitz property, we design a nonlinear feedback linearization controller using the learned model and prove system stability with disturbance rejection. To the best of our knowledge, this is the first DNNbased nonlinear feedback controller with stability guarantees that can utilize arbitrarily large neural nets. Experimental results demonstrate that the proposed controller significantly outperforms a Baseline Nonlinear Tracking Controller in both landing and cross-table trajectory tracking cases. We also empirically show that the DNN generalizes well to unseen data outside the training domain.
In this paper, we present Neural-Swarm, a nonlinear decentralized stable controller for close-proximity flight of multirotor swarms. Close-proximity control is challenging due to the complex aerodynamic interaction effects between multirotors, such as downwash from higher vehicles to lower ones. Conventional methods often fail to properly capture these interaction effects, resulting in controllers that must maintain large safety distances between vehicles, and thus are not capable of close-proximity flight. Our approach combines a nominal dynamics model with a regularized permutation-invariant Deep Neural Network (DNN) that accurately learns the high-order multi-vehicle interactions. We design a stable nonlinear tracking controller using the learned model. Experimental results demonstrate that the proposed controller significantly outperforms a baseline nonlinear tracking controller with up to four times smaller worst-case height tracking errors. We also empirically demonstrate the ability of our learned model to generalize to larger swarm sizes.
Single cell analysis has received increasing attention recently in both academia and clinics, and there is an urgent need for effective upstream cell sample preparation. Two extremely challenging tasks in cell sample preparation-highefficiency cell enrichment and precise single cell capture-have now entered into an era full of exciting technological advances, which are mostly enabled by microfluidics. In this review, we summarize the category of technologies that provide new solutions and creative insights into the two tasks of cell manipulation, with a focus on the latest development in the recent five years by highlighting the representative works. By doing so, we aim both to outline the framework and to showcase example applications of each task. In most cases for cell enrichment, we take circulating tumor cells (CTCs) as the target cells because of their research and clinical importance in cancer. For single cell capture, we review related technologies for many kinds of target cells because the technologies are supposed to be more universal to all cells rather than CTCs. Most of the mentioned technologies can be used for both cell enrichment and precise single cell capture. Each technology has its own advantages and specific challenges, which provide opportunities for researchers in their own area. Overall, these technologies have shown great promise and now evolve into real clinical applications. Published by AIP Publishing. [http://dx
There are still some problems need to be solved though there are a lot of achievements in the fields of automatic driving. One of those problems is the difficulty of designing a car-following decision-making system for complex traffic conditions. In recent years, reinforcement learning shows the potential in solving sequential decision optimization problems. In this article, we establish the reward function R of each driver data based on the inverse reinforcement learning algorithm, and r visualization is carried out, and then driving characteristics and following strategies are analyzed. At last, we show the efficiency of the proposed method by simulation in a highway environment.
We present Neural-Swarm2, a learning-based method for motion planning and control that allows heterogeneous multirotors in a swarm to safely fly in close proximity. Such operation for drones is challenging due to complex aerodynamic interaction forces, such as downwash generated by nearby drones and ground effect. Conventional planning and control methods neglect capturing these interaction forces, resulting in sparse swarm configuration during flight. Our approach combines a physics-based nominal dynamics model with learned Deep Neural Networks (DNNs) with strong Lipschitz properties. We evolve two techniques to accurately predict the aerodynamic interactions between heterogeneous multirotors: i) spectral normalization for stability and generalization guarantees of unseen data and ii) heterogeneous deep sets for supporting any number of heterogeneous neighbors in a permutation-invariant manner without reducing expressiveness. The learned residual dynamics benefit both the proposed interaction-aware multi-robot motion planning and the nonlinear tracking control designs because the learned interaction forces reduce the modelling errors. Experimental results demonstrate that Neural-Swarm2 is able to generalize to larger swarms beyond training cases and significantly outperforms a baseline nonlinear tracking controller with up to three times reduction in worst-case tracking errors. Video is available at https://youtu.be/Y02juH6BDxo.
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