Efficient Desilylation of Some Nucleoside Derivatives with Potassium tert-Butoxide in Dimethylformamide.-The new method for desilylation of nucleosides does not require aqueous work-up and gives high yields. -(NEGRON, G.; VASQUEZ, F.; CALDERON, G; CRUZ, R.; GAVINO, R.; ISLAS, G.; Synth.
The relevance of the use of mpMRI (multiparameter prostate magnetic resonance imaging) to evaluate the prostate in the context of PCa diagnosis lies in its ability to visualize primarily high-grade cancerous lesions that may be missed in routine diagnostic biopsies. standard. In several studies, mpMRI has shown improved performance compared to clinical models in identifying candidates who will benefit most from different therapies such as SA. Although data on mpMRI of the prostate during follow-up in men undergoing SA are sparse, there is potential to significantly improve AS programs through more accurate selection of optimal candidates which could achieve more accurate identification of progression of prostate cancer. disease and a reduction in the number of biopsies that would be needed to retest patients.
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