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2018 JINST 13 P05011 8.5 Measurement of the data-to-simulation scale factors as a function of the discriminator value 76 8.6 Comparison of the measured data-to-simulation scale factors 79 9 Measurement of the tagging efficiency for boosted topologies 82 9.1 Comparison of data with simulation 82 9.2 Efficiency for subjets 83 9.2.1 Misidentification probability 83 9.2.2 Measurement of the b tagging efficiency 84 9.3 Efficiency of the double-b tagger 86 9.3.1 Measurement of the double-b tagging efficiency 86 9.3.2 Measurement of the misidentification probability for top quarks 87

Combined measurements of the production and decay rates of the Higgs boson, as well as its couplings to vector bosons and fermions, are presented. The analysis uses the LHC proton–proton collision data set recorded with the CMS detector in 2016 at , corresponding to an integrated luminosity of 35.9 . The combination is based on analyses targeting the five main Higgs boson production mechanisms (gluon fusion, vector boson fusion, and associated production with a or boson, or a top quark-antiquark pair) and the following decay modes: , , , , , and . Searches for invisible Higgs boson decays are also considered. The best-fit ratio of the signal yield to the standard model expectation is measured to be , assuming a Higgs boson mass of . Additional results are given for various assumptions on the scaling behavior of the production and decay modes, including generic parametrizations based on ratios of cross sections and branching fractions or couplings. The results are compatible with the standard model predictions in all parametrizations considered. In addition, constraints are placed on various two Higgs doublet models.