Large seasonal water-level fluctuations may influence isotopic signatures of primary producers and the types and amounts of these potential food sources accessible to aquatic fauna of Poyang Lake, the largest freshwater lake in China. In this study, the isotopic signatures of primary producers and consumers were determined, stable carbon and nitrogen isotope analysis and mixing models were combined to investigate the influence of water levels on the diet and isotopic composition of Poyang Lake fish and invertebrates. Five potential food sources (seston, benthic organic matter, aquatic macrophytes, attached algae, and terrestrial plants), 4 species of invertebrates, and 10 species of fish were collected from the lake area during dry and wet seasons between January

Background/Aims: Psoralen and bakuchiol are the main active compounds found in the traditional Chinese medicine Psoralea corylifolia L., and have been used to treat osteoporosis. This study aims to investigate the anti-osteoporosis effects of these two compounds using osteoclasts precursor differentiation and bone absorption assays in vitro. Methods: Primary mouse osteoclasts precursor cells were induced by M-CSF (macrophage colony stimulating factor) plus RANKL (receptor activator of nuclear factor kappa-B ligand) in vitro. TRACP (tartrate-resistant acid phosphatase) enzyme activity and toluidine blue staining were used to observe the effects of psoralen and bakuchiol on osteoclast differentiation and bone resorption, respectively. Gelatin zymography was used to assess MMP (matrix metalloproteinase) activity, and ELISA was performed to measure cathepsin K activity. Western blotting analysis for expression of phosphorylated AKT, ERK, NF-kB, and c-jun; and immunofluorescence analysis for c-jun and p65 nuclear translocation in induced osteoclasts were then used to determine the mechanism of anti-bone resorption of psoralen and bakuchiol. Results: Mature osteoclasts were induced by M-CSF plus RANKL from primary bone marrow macrophages in vitro. Both psoralen and bakuchiol significantly inhibited TRACP enzyme activity and slightly decreased the number of TRACP⁺ multinuclear osteoclasts induced by M-CSF plus RANKL. Bakuchiol significantly decreased bone lacunae area and attenuated MMP-2 activity induced by M-CSF plus RANKL in osteoclasts. Both psoralen and bakuchiol significantly decreased the expression and nuclear translocation of phosphorylated c-jun stimulated by M-CSF plus RANKL, but no significant effect on p65 translocation was observed in osteoclasts. Additionally, bakuchiol significantly attenuated the increased of M-CSF plus RANKL-induced phosphorylation of AKT in osteoclasts. Conclusions: Psoralen and bakuchiol ameliorated M-CSF plus RANKL-induced osteoclast differentiation and bone resorption via inhibition of AKT and AP-1 pathways activation in vitro.

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In disaster recovery, ground network consisting of mobile terminals of rescue vehicles and civilians may be disconnected due to severe environment. In this situation, multiple unmanned aerial vehicles (UAVs) form an aerial network to enhance the connectivity of the ground network. When two nodes in ground network are disconnected, they adopt UAVs as relays to transmit data. Otherwise, they communicate with device-to-device manner. With this framework, the coverage probability of these two kinds of users is analysed. Besides, the optimal altitude of UAVs to maximise the capacity of ground network is achieved. A guideline is provided for the design of multiple UAVs support wireless network.

We propose a new integrated target tracking, recognition and segmentation algorithm, called ATR-Seg, for infrared imagery. ATR-Seg is formulated in a probabilistic shape-aware level set framework that incorporates a joint view-identity manifold (JVIM) for target shape modeling. As a shape generative model, JVIM features a unified manifold structure in the latent space that is embedded with one view-independent identity manifold and infinite identity-dependent view manifolds. In the ATR-Seg algorithm, the ATR problem formulated as a sequential level-set optimization process over the latent space of JVIM, so that tracking and recognition can be jointly optimized via implicit shape matching where target segmentation is achieved as a by-product without any pre-processing or feature extraction. Experimental results on the recently released SENSIAC ATR database demonstrate the advantages and effectiveness of ATR-Seg over two recent ATR algorithms that involve explicit shape matching.

The tribological characteristics of PEEK composites fretting against GCr 15 steel were investigated by a SRV-IV oscillating reciprocating ball-on-disk tribometer. In order to clarify the effect of type and size of fillers on the properties of PEEK composites, nano-sized and micro-sized CF and PTFE fillers were added to the PEEK matrix. The thermal conductivity, hardness, and fretting wear properties of PEEK composites reinforced by CF or PTFE were comparatively studied. The results showed that the type and size of the fillers have an important effect on both the friction coefficient and wear rate, by affecting their thermal conductivity, hardness, as well as the surface areas of their transfer films. In comparison, the effect on improving the tribological properties of micro-sized CF was superior to that of nano-sized CF, while the effect of nano-sized PTFE was superior to that of micro-sized PTFE. Considering the acceptable friction coefficient and wear rate of the composite under the fretting wear test, it seemed that 4% nCF, 20% mCF, 2% nPTFE and 10% mPTFE were desired additive proportions. And it also can be found that during the fretting wear test, the abrasive and adhesive wear resulted in accumulative debris at the contacting surface. The transfer films made of debris were formed on the counterfaces.

We characterize the seismic events that occurred in North Korea on 9 September 2016 and South Korea on 12 September 2016. The 9 September 2016 event was identified as an explosion, and the two 12 September 2016 events were identified as natural earthquakes using the P/S (P-and S-wave) spectral ratios, Pg/Lg, Pn/Lg, and Pn/Sn as discriminants. The explosive event was relocated within the North Korean nuclear test site using a relative location method and the 2006 North Korea underground nuclear test as the master event, and the epicenter was identified at 41.2976°N latitude and 129.0804°E longitude. From the regional Lg and Rayleigh waves, the body-and surface-wave magnitudes for the 9 September 2016 event were calculated as m b Lg 4:8 0:2 and M s 4:2 0:1. By adopting an empirical magnitude-yield relation for the body-wave magnitude, and assuming that the explosion was fully coupled and detonated at a normally scaled depth, we estimated that the seismic yield was ∼6 kt, and the uncertainty range was between 3 and 11 kt. If an overburied depth range between 780 and 1200 m was applied, then the yield would be increased to 16-22 kt. Electronic Supplement: Figures comparing the vertical seismograms for events occurring on 9 and 12 September 2016; spectral ratios from individual stations and events; Pn-waveform cross correlations at selected stations and vertical Rayleigh waveforms from NKT5 recorded at station HIA; and tables of the cross-correlation parameters of the Pn waveforms, residuals of Pn differential travel times, and event parameters used in this study.