The purpose of this review was to provide an update of research findings on employers' attitudes toward workers with disabilities. Fifteen studies published in the last decade were examined. It was found that employers showed positive general attitudes toward workers with disabilities, but had some reservations toward hiring workers with certain types of disabilities. Positive past experiences with individuals with disabilities were associated with more willingness to hire and retain employees with disabilities. However, fewer concerns were identified in this review than previous reviews.
The excited-state intramolecular proton transfer
(ESIPT) of 2-(2‘-hydroxyphenyl)benzimidazole (HBI)
has
been studied using absorbance, steady-state, and time-resolved emission
spectroscopies in cyclodextrins (β-,
γ-, and 2,6-di-O-methyl-β-cyclodextrins) and in binary
aqueous solvent mixtures. The spectral
characteristics
of HBI in cyclodextrins and binary solvent mixtures (dioxane:water,
MeOH:water, and solutions of cyclohexane
containing MeOH and trifluoroethanol) are compared to further study the
effects of various microenvironments
on the ground and excited-state properties of the molecule. The
intermolecular interactions of HBI with
cyclodextrins and various solvents appear to weaken intramolecular
hydrogen bonding in HBI and facilitate
the formation of strong intermolecular hydrogen bonds with the various
cyclodextrins and solvent molecules.
The acquired data are used to suggest the formation of a
zwitterionic structure of HBI in cyclodextrins.
The effects of α-, β- , γ-, and
2,6-di-O-methyl-β-cyclodextrins (CDs) on the ground- and
excited-state properties
of 2-(2‘-hydroxyphenyl)benzoxazole,
2-(2‘-hydroxyphenyl)benzothiazole, and
2-(2‘-hydroxyphenyl)benzimidazole in aqueous media are investigated. Steady-state
fluorescence measurements are used to characterize
the interaction of CDs with these azoles. Absorbance measurements
indicate increased solubility of the azoles
in aqueous solutions of CDs. Measurements of acidity constants
(pK
a) and data from induced circular
dichroism
indicate increased ground- and excited-state acidities of the phenolic
protons of the molecules in the presence
of CDs and axial orientation of the molecules within the CD cavity,
respectively. The data further suggest
a planar stucture for HBO and a twisted confirmation for both HBT and
HBI. The association constants of
the inclusion complexes have also been estimated. These studies
are further supplemented by comparative
spectroscopic studies of 2-(2‘-methoxyphenyl)benzothiazole in
aqueous solutions of CDs. On the basis of
the spectral data acquired, it is believed that the HBA molecules exist
as zwitterionic tautomers in the presence
of CDs.
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