Pressure drop (p) and collection efficiency (η) are used to evaluate the separation performance of the cyclone separator. In this study, we conducted comparative study of cyclone models using response surface methodology (RSM), back propagation neural network (BPNN), and group method of data handling (GMDH) networks to develop optimal predictive cyclone models. Also, we conducted multi-objective optimization for maximizing model and minimizing model using genetic algorithm (GA). CFD was performed instead of experimental method to get the estimated values for modeling of p and η. The validation results of CFD showed 0.5% and 2% errors for p and η, respectively, compared with the experimental data. Second, design of experiment (DOE) analysis for 10 cyclone geometrical parameters was executed to obtain the significant geometrical parameters. Vortex finder diameter D x , inlet width a, inlet height b and cone height H co have a significant effect on η and p. However, interaction effects between the geometrical parameters have small effects. The cyclone models by RSM, BPNN and GMDH based on 25 CFD training set were developed. The predictive performance results by the cyclone models were compared by 25 CFD test set. The GMDH method achieved the best prediction for p (R 2 = 99.7, RMSE = 0.102) R 2 adjusted = 98.99, RMSE = 0.0119) than the RSM, BPNN cyclone models. Additionally, uncertainty analysis was performed to estimate the quantitative performance of cyclone models. The results show that the uncertainty width of GMDH models achieved the best prediction (η: ±0.0065, p: ±0.0188). Finally, GA was applied to optimize the GMDH models simultaneously. GA generated 70 non-dominant solutions. Reproducibility of five optimal points was validated by using CFD. The trade-off optimal point showed improvement by 24.31%, 18% and 8.79% for p d 50 and η, respectively.
As the prevalence of diabetes increases, millions of people need to be screened for diabetic retinopathy (DR). Remarkable advances in technology have made it possible to use artificial intelligence to screen DR from retinal images with high accuracy and reliability, resulting in reducing human labor by processing large amounts of data in a shorter time. We developed a fully automated classification algorithm to diagnose DR and identify referable status using optical coherence tomography angiography (OCTA) images with convolutional neural network (CNN) model and verified its feasibility by comparing its performance with that of conventional machine learning model. Ground truths for classifications were made based on ultra-widefield fluorescein angiography to increase the accuracy of data annotation. The proposed CNN classifier achieved an accuracy of 91–98%, a sensitivity of 86–97%, a specificity of 94–99%, and an area under the curve of 0.919–0.976. In the external validation, overall similar performances were also achieved. The results were similar regardless of the size and depth of the OCTA images, indicating that DR could be satisfactorily classified even with images comprising narrow area of the macular region and a single image slab of retina. The CNN-based classification using OCTA is expected to create a novel diagnostic workflow for DR detection and referral.
In this paper, the characteristics of the cyclone separator was analyzed from the Lagrangian perspective for designing the important dependent variables. The neural network network model was developed for predicting the separation performance parameter. Further, the predictive performances were compared between the traditional surrogate model and the developed neural network model. In order to design the important parameters of the cyclone separator based on the particle separation theory, the force acting until the particles are separated was calculated using the Lagrangian-based computational fluid dynamics (CFD) methodology. As a result, it was proved that the centrifugal force and drag acting on the critical diameter having a separation efficiency of 50% were similar, and the particle separation phenomenon in the cyclone occurred from the critical diameter, and it was set as an important dependent variable. For developing a critical diameter prediction model based on machine learning and multiple regression methods, unsteady-Reynolds averaged Navier-Stokes analyzes according to shape dimensions were performed. The input design variables for predicting the critical diameter were selected as four geometry parameters that affect the turbulent flow inside the cyclone. As a result of comparing the model prediction performances, the machine learning (ML) model, which takes into account the critical diameter and the nonlinear relationship of cyclone design variables, showed a 32.5% improvement in R-square compared to multi linear regression (MLR). The proposed techniques have proven to be fast and practical tools for cyclone design.
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