Body Area Networks (BANs) are expected to play a major role in patient health monitoring in the near future. Providing an efficient key agreement with the prosperities of plugn-play and transparency to support secure inter-sensor communications is critical especially during the stages of network initialization and reconfiguration. In this paper, we present a novel key agreement scheme termed Ordered-Physiological-Feature-based Key Agreement (OPFKA), which allows two sensors belonging to the same BAN to agree on a symmetric cryptographic key generated from the overlapping physiological signal features, thus avoiding the pre-distribution of keying materials among the sensors embedded in the same human body. The secret features computed from the same physiological signal at different parts of the body by different sensors exhibit some overlap but they are not completely identical. To overcome this challenge, we detail a computationally efficient protocol to securely transfer the secret features of one sensor to another such that two sensors can easily identify the overlapping ones. This protocol possesses many nice features such as the resistance against brute force attacks. Experimental results indicate that OPFKA is secure, efficient, and feasible. Compared with the state-of-the-art PSKA protocol, OPFKA achieves a higher level of security at a lower computational overhead.Index Terms-Body Area Networks (BANs); secure intersensor communications; Inter-Pulse-Interval (IPI); physiological feature based key agreement.
BackgroundThe TNM staging system is based on three anatomic prognostic factors: Tumor, Lymph Node and Metastasis. However, cancer is no longer considered an anatomic disease. Therefore, the TNM should be expanded to accommodate new prognostic factors in order to increase the accuracy of estimating cancer patient outcome. The ensemble algorithm for clustering cancer data (EACCD) by Chen et al. reflects an effort to expand the TNM without changing its basic definitions. Though results on using EACCD have been reported, there has been no study on the analysis of the algorithm. In this report, we examine various aspects of EACCD using a large breast cancer patient dataset. We compared the output of EACCD with the corresponding survival curves, investigated the effect of different settings in EACCD, and compared EACCD with alternative clustering approaches.ResultsUsing the basic T and N definitions, EACCD generated a dendrogram that shows a graphic relationship among the survival curves of the breast cancer patients. The dendrograms from EACCD are robust for large values of m (the number of runs in the learning step). When m is large, the dendrograms depend on the linkage functions.The statistical tests, however, employed in the learning step have minimal effect on the dendrogram for large m. In addition, if omitting the step for learning dissimilarity in EACCD, the resulting approaches can have a degraded performance. Furthermore, clustering only based on prognostic factors could generate misleading dendrograms, and direct use of partitioning techniques could lead to misleading assignments to clusters.ConclusionsWhen only the Partitioning Around Medoids (PAM) algorithm is involved in the step of learning dissimilarity, large values of m are required to obtain robust dendrograms, and for a large m EACCD can effectively cluster cancer patient data.
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