-Species within the genus, Campylobacter, have emerged over the last three decades as significant clinical pathogens, particularly of human public health concern, where the majority of acute bacterial enteritis in the Western world is due to these organisms. Of particular concern are the species, C. jejuni and C. coli, which are responsible for most of these gastrointestinal-related infections. Although these organisms have already emerged as causative agents of zoonoses, several aspects of their epidemiology and pathophysiology are only beginning to emerge. Trends in increasing antibiotic resistance are beginning to emerge with oral antibiotics, which may be the drug of choice for when it is necessary to intervene chemotherapeutically. This review wishes to examine (i) emerging clinical aspects of the disease, such as Guillain Barré syndrome (GBS), (ii) the association between these organisms and poultry as a natural host, (iii) environmental aspects of Campylobacter epidemiology, (iv) the emergence of atypical campylobacters (v) emerging trends in antibiotic resistance, (vi) adoption of modern methods for the detection of campylobacters.

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This study investigated the possibility that sublethal food preservation stresses (high or low temperature and osmotic and pH stress) can lead to changes in the nature and scale of antibiotic resistance (ABR) expressed by three food-related pathogens (Escherichia coli, Salmonella enterica serovar Typhimurium, and Staphylococcus aureus). The study found that some sublethal stresses significantly altered antibiotic resistance. Incubation at sublethal high temperature (45°C) decreased ABR. Incubation under increased salt (>4.5%) or reduced pH (<5.0) conditions increased ABR. Some of the pathogens continued to express higher levels of ABR after removal of stress, suggesting that in some cases the applied sublethal stress had induced stable increases in ABR. These results indicate that increased use of bacteriostatic (sublethal), rather than bactericidal (lethal), food preservation systems may be contributing to the development and dissemination of ABR among important food-borne pathogens.

Aims: In the past eight to 10 years, reports of antibiotic resistance in food‐borne isolates in many countries have increased, and this work examined the susceptibility of 1001 food isolates of Listeria species. Methods and Results: Susceptibility/resistance to eight antibiotics was determined using the Bauer–Kirby disc diffusion assay, and 10·9% of the isolates examined displayed resistance to one or more antibiotics. Resistance to one or more antibiotics was exhibited in 0·6% of Listeria monocytogenes isolates compared with 19·5% of Listeria innocua isolates. Resistance was not observed in Listeria seeligeri or Listeria welshimeri. Resistance to tetracycline (6·7%) and penicillin (3·7%) was the most frequently observed, and while resistance to one antibiotic was most common (9·1%), isolates resistant to two or more antibiotics (1·8%) were also observed. Conclusions: While resistance to the antibiotics most commonly used to treat human listeriosis was not observed in L. monocytogenes, the presence of such resistance in other Listeria species raises the possibility of future acquisition of resistance by L. monocytogenes. Significance and Impact of the Study: The higher level of resistance in L. innocua compared with L. monocytogenes suggests that a species‐related ability to acquire resistance to antibiotics exists.

The‐survival‐characteristics‐of‐a‐non‐toxigenic,‐antibiotic‐resistant‐strain‐of‐Escherichia‐coli‐O157:H7‐in‐bovine‐faeces‐were‐investigated.‐Faecal‐samples‐were‐inoculated‐with 108‐9‐cfu‐g−1‐of‐the‐organism‐and‐(i)‐stored‐in‐closed‐plastic‐containers‐at‐10 °C, (ii) stored in closed plastic containers placed outside or (iii) decanted onto the surface of grazing land. Recovery and enumeration on Sorbitol MacConkey Agar (SMAC) and Tryptic Soya Agar (TSA) revealed that the E. coli O157:H7 numbers in both enclosed samples (i and ii) had decreased by 4·5–5·5 log10 cfu g−1 within 99 d. Numbers in samples decanted onto grassland (iii) decreased by 4·0–5·0 log10 cfu g−1 within 50 d but the organism was still detectable in the surrounding soil for up to 99 d. Persistence of E. coli O157:H7 in bovine faeces and contaminated pastures may therefore be an important factor in the initial infection and re‐infection of cattle.