The bronchial stump fistula shown by patients undergoing adjusted pulmonary resections is an extremely severe condition affecting the prognosis of this patients. Within our study, we have used an innovative technique of closing the bronchial stump for 38 patients undergoing adjusted pulmonary resections. The suture of the bronchial stump was made through an innovative method, by practicing the suture with isolated 2.0 Prolene wires armed with patches of Polypropylene. The incidence of the bronchial stump fistula for the observed lot was of 5.26% (2 cases), smaller than the one reported in the specialty literature. In this respect, we consider that the use of Polypropylene in the techniques of closing the bronchial blunt can be beneficial.

Intravenous leiomyoma is a benign smooth muscle cell tumor of uterine origin that may grow into the pelvic veins and the inferior vena cava. It usually affects premenopausal women and the majority (90%) are parous. Because cardiac involvement is present in up to 10% of cases, it may be misdiagnosed as a primary cardiac tumor or a venous thrombus-in-transit. We describe a case of intravascular leiomyomatosis with cardiac extension and the morphological particularities of the removed tumor.

PURPOSE:To assess whether deoxycholic acid (DOC) and lithocholic acid (LCA) administered in a period of six months in a concentration of 0.25% may have a carcinogenic role in mice colon. METHODS:The study used C57BL6 female mice divided into four groups. The control group received a balanced diet and the others received diets supplemented with 0.25% DOC, 0.25% LCA and 0.125% DOC+0.125% LCA, respectively. After euthanasia, the lesions found in the resected gastrointestinal tracts were stained with hematoxylin-eosin and examined microscopically. RESULTS:No gastrointestinal tract changes were observed in the control group, while hyperplastic Peyer's patches in the small intestine, flat adenomas with mild dysplasia and chronic colitis at the level of the colon were found in all three test groups. The colonic lesions prevailed in the proximal colon. The highest number of flat adenoma lesions (8), hyperplasia of Peyer's patches (25) and chronic colitis (2) were found in mice fed with diet and LCA. CONCLUSION:Precancerous or cancerous pathological lesions could not be identified. Instead, adenomatous colonic injuries occurred in a shorter period of time (six months), compared to the reported data.

BACKGROUND Primary choriocarcinoma of the stomach (PCCS) is a rare tumor, with fewer than 60 cases published in the English-language literature up to December 2018. In this paper, we present the complex immunoprofile of one PCCS and a hypothesis regarding its histogenesis. CASE SUMMARY A 66-year-old previously healthy male underwent an emergency palliative gastrectomy for a gastric obstructive tumor. The histologic examination and immunoprofile of tumor cells showed a mixed tumor that consisted of choriocarcinoma (90%) and moderate differentiated adenocarcinoma (10%), with hepatic metastases (Stage pT2NxM1L1V1R0) and microsatelite stable status. The patient died one month after surgery. The tumor cells showed focal positivity for CDX2 (adenocarcinoma component), HCG (choriocarcinoma) and CD138 (plasmacytoid carcinoma component) and were negative for HER-2, α-fetoprotein, VEGF, maspin and markers of epithelial-mesenchymal transition. The gastric mucosa cells displayed positivity for CDX2, Hepar A and CD138. The complex immunoprofile and literature data synthesis prove that the gastric mucosa cells can present a multilineage differentiation. CONCLUSION PCCS should be considered as an aggressive variant of microsatellite stable gastric adenocarcinoma of an epithelial type, and not a germ cell tumor.

The thoracic wall resections for tumoral affections are laborious surgical interventions characterized by a high mortality and mobility. In order to create this paper we created a observational retrospective study in which we included 21 patients that have underwent parietal thoracic resections for tumoral affections. In all the patients we practiced the reconstruction of the thoracic wall using polypropylene mesh. The main postoperative complications were: seromas (14.28% of the cases), hematomas (9.52% of the cases), wound infection (4.76% of the cases), pneumonia (23.8% of the cases), respiratory failure (23.8% of the cases), paradoxical movement of the thoracic wall (52.38% of the cases). No deceases were recorded. In conclusion, the use of polypropylene mesh in the reconstructive techniques of the thoracic wall after thoracic wall resection represents a viable method, with good respiratory functional results.