DW-MRI exhibits high diagnostic performance in bladder cancer with excellent objectivity. The ADC value could potentially serve as a biomarker to predict clinical aggressiveness in bladder cancer.

A search for isomeric γ-decays among fission fragments from 345 MeV/nucleon 238 U has been performed at the RIKEN Nishina Center RI Beam Factory. Fission fragments were selected and identified using the superconducting in-flight separator BigRIPS and were implanted in an aluminum stopper. Delayed γ-rays were detected using three clover-type high-purity germanium detectors located at the focal plane within a time window of 20 μs following the implantation. We identified a total of 54 microsecond isomers with half-lives of ~ 0. on the obtained spectroscopic information and the systematics in neighboring nuclei. Nature of the nuclear isomerism is discussed in relation to evolution of nuclear structure.KEYWORDS: Nuclear reactions Be( 238 U, x) and Pb( 238 U, x) E = 345 MeV/nucleon, in-flight fission, fission fragments, in-flight RI beam separator, short-lived isomers, new isomers, half-life, γ-ray relative intensity, γγ coincidence, proposed level schemes DOI: PACS number(s): 23.35.+g, 23.20.Lv, 29.38.Db _____________________ *

ADC value would reflect T stage and Ki-67 LI, representing invasive and proliferative potential, respectively. ADC value is likely to serve as a biomarker reflecting aggressiveness of bladder cancer.

A search for new isotopes using in-flight fission of a 345 MeV/nucleon 238 U beam has been carried out at the RI Beam Factory at the RIKEN Nishina Center. Fission fragments were analyzed and identified by using the superconducting in-flight separator BigRIPS. We observed 45 new neutron-rich isotopes: Since the pioneering production of radioactive isotope (RI) beams in the 1980s, 1) studies of exotic nuclei far from stability have been attracting much attention. Neutron-rich exotic nuclei are of particular interest, because new phenomena such as neutron halos, neutron skins, and modifications of shell structure have been discovered.2-5) Furthermore these neutron-rich nuclei are important in relation to astrophysical interests, 6) because many of them play a role in the astrophysical r-process. 7) To make further advances in nuclear science and nuclear astrophysics, it is essential to expand the region of accessible exotic nuclei towards the neutron dripline. In-flight fission of a uranium beam is known to be an excellent mechanism for this purpose, having large production cross sections for neutron-rich exotic nuclei. became operational, in which the superconducting in-flight separator BigRIPS 10,11) has been used for the production of RI beams. The BigRIPS separator is designed as a two-stage separator with large acceptance, so that excellent features of in-flight fission can be exploited. In May 2007, right after the commissioning of the BigRIPS separator, we performed an experiment to search for new isotopes using in-flight fission of a 345 MeV/nucleon 238 U beam, aiming to expand the LETTERS Ã

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