IntroductionThe relationship between human immunodeficiency virus (HIV) and malnutrition is easily explained, and the etiology of malnutrition in HIV disease is believed to be multifactorial.It therefore follows that ongoing assessment of nutritional and medical status is crucial to quality nutrition care for every person living with HIV. The aim of this study was to find out the effect of nutritional counseling and monitoring, using personalized dietary prescriptions, on the body mass index (BMI) and hemoglobin of patients who are HIV-infected and also receiving highly active antiretroviral drugs.MethodsA total of 84 patients were selected using simple random sampling and allocated into intervention and control groups. Nutritional counseling and monitoring was done for the intervention group, while only weight, height, and hemoglobin concentration were monitored for the control group. At the end of 6 months, the differences in mean body mass index (BMI) and hemoglobin concentrations of the intervention and control groups were compared using the Student’s t-test. Statistical level of significance was put at P<0.05.ResultsAmong respondents, 30.96% were males and 69.04% were females, and the mean age of the intervention group was 33.8 years and was 35.3 in the control group. After 6 months of study, the difference in the mean BMI among the males of both groups (24.9 kg/m2 [intervention] and 24.3 kg/m2 [control]) was not significant (P=0.53) but was significant among the females (24.9 kg/m2 [intervention group] versus 21.8 kg/m2 [control group]) (P=0.0005). The difference in mean hemoglobin concentration between the intervention and control groups for both males and females were statistically significant (12.2 mg/dL for males in the intervention group and 11.0 mg/dL for males in the control group [P=0.005]; 11.9 mg/dL for females in the intervention group and 11.0 mg/dL for females in the control group [P=0.010ConclusionNutrition intervention is important in the management of people living with HIV/acquired immunodeficiency disease (AIDS) while on antiretroviral therapy. This can be achieved through nutritional counseling and monitoring.

Background: Lassa fever is a viral hemorrhagic fever found predominantly in West Africa with the potential to cause approximately 5,000 deaths per year. However, good knowledge of the disease may reduce the infection rate. The study assessed the knowledge of Lassa fever and its determinants among traders in Izzi community Ebonyi State, Nigeria. Methods: A descriptive cross-sectional study was conducted among 248 traders selected by simple random sampling method. Data were collected from respondents who gave their informed consent using interviewer-administered semi-structured questionnaire and analyzed using Chisquare test (Fisher's exact test where appropriate) for categorical variables and binary logistic regression for predictors of the outcome variables. Statistical significance was set at p < 0.05 Results: Most of the respondents (40%) were within the age group of 21 -30 years. Majority of the Original Research Articletraders were females (64.1%), married (64.1%) and predominantly Christians (97.2%). A large proportion of the respondents (43.1%) had secondary education level, and 10.1% had no formal education. Awareness of Lassa fever was high 197 (79.4%) among the traders. The commonest source of information was radio 152 (61.3%), and only 15% of the respondents heard about Lassa fever from health workers. Overall knowledge of Lassa fever was poor: 173 (70%) of the traders had poor knowledge, and only 53 (21.4%) had excellent knowledge. Majority of the traders 160 (64.5%) ate rat's meat. Factors found to be significantly associated with knowledge of Lassa fever include gender, educational status, and consumption of rat. Predictors of adequate knowledge include male gender and completing tertiary education. Conclusion:The high level of awareness of Lassa fever in this study did not translate to adequate knowledge of the disease. The poor level of knowledge points towards a growing need to step up not just awareness of Lassa fever but also in-depth knowledge of the causes, mode of transmission and prevention of the disease through public education with special access to the female cohort.

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Background The rate of diagnostic testing for malaria is still very low in Nigeria despite the scale-up of malaria rapid diagnostic test (MRDT) availability, following WHO's recommendation of universal diagnostic testing in 2010. We investigated whether a social group sensitisation and education intervention (social group intervention) and a social group intervention plus health-care provider training intervention would increase the demand (use or request, or both) for MRDTs among community members in Ebonyi state, Nigeria. MethodsWe did a three-arm, parallel, open-label, stratified cluster-randomised controlled trial in Ebonyi state, Nigeria, to evaluate the effects of two interventions compared with a control. We randomly assigned geographical clusters that were accessible (close to a road that was drivable even during the rainy seasons) and had at least one eligible public primary health facility and patent medicine vendor (those that offered MRDT services) in a 1:1:1 allocation to the control arm (receiving no intervention), social group arm (receiving sensitisation and education about MRDT), or social group plus provider arm (receiving the social group intervention plus provider training in health communication about MRDT). Investigators, participants (social groups, providers, respondents), and interviewers could not be masked to group assignments. The primary outcome was the proportion of children younger than 5 years with fever or malaria-like illness, in the 2 weeks preceding a household survey, who received an MRDT, and the coprimary outcome was the same outcome but among children aged 5 years and older (ie, up to and including 17 years) and adults (excluding pregnant women). The outcomes were measured at an individual level via household surveys before the interventions and 3 months after the end of the interventions. All analyses were done using a cluster-level method on an intention-to-treat basis. This trial is registered with ISRCTN, number ISRCTN14046444. FindingsWe carried out eligibility screening and recruitment of participants (clusters, social groups, and providers) between July 2 and Sept 27, 2018. 34 clusters met the eligibility criteria and 18 were randomly selected to participate and randomly assigned to arms (six clusters per arm). A mean proportion of 40•6% (SD 14•5) of eligible children younger than 5 years in the control arm received an MRDT, versus 66•7% (11•7) in the social group arm (adjusted risk difference [aRD] 28•8%, 95% CI 21•9-35•7, p<0•0001) and 71•7% (19•8) in the social group plus provider arm (aRD 32•7%, 24•9-40•5, p<0•0001), with no significant difference between the social group arm and the social group plus provider arm. A mean proportion of 36•3% (18•5) of eligible children aged 5 years and older in the control arm received an MRDT, versus 60•7% (14•0) in the social group arm (aRD 25•6%, 16•8-34•4, p=0•0004), and 59•5% (18•3) in the social group plus provider arm (aRD 28•0%, 19•5-36•5, p=0•0002), with no significant difference between the social group arm and the soci...

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