Puerarin suppresses the NF-κB signaling pathway by activating the Nrf2/HO-1 axis, thereby inhibiting IL-1β-induced inflammation and ECM degradation in Osteoarthritis.
Osteoarthritis is a chronic degenerative disease characterized by the destruction of cartilage. It is the fourth most disabling disease in the world and is currently incurable. Inflammation and extracellular matrix...
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