Basem T. Jamal scite author profile

Background: Increased protein N-glycosylation and aberrant Wnt signaling are features of oral cancer. Results: Overexpression of pro-migratory protein CTHRC1 is due to hyperglycosylation and transcriptional activation by canonical Wnt. Conclusion: N-Glycosylation collaborates with canonical Wnt to induce CTHRC1 and drive OSCC cell migration. Significance: Elucidating how N-glycosylation impacts tumor-promoting proteins is critical to understand cancer development and progression.

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Basem T. Jamal

Ophthalmic Injuries in Patients With Zygomaticomaxillary Complex Fractures Requiring Surgical Repair

N-Glycosylation Induces the CTHRC1 Protein and Drives Oral Cancer Cell Migration

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