53(4) LRTS 231 This review covers the literature of acquisitions from 2004 through 2007. The purchase of electronic resources continued to grow, especially for e-journals. E-books gained more attention with a variety of pricing models emerging, many of which were similar to print purchase plans or a modification of e-serial plans. The electronic resource management (ERM) of subscriptions and licensing became a major concern as the acquisition of these items continued to grow. Many libraries developed local ERM applications while vendors began developing commercial ERM systems. The Digital Library Federation (DLF) Electronic Resources Management Initiative (ERMI) emerged as a major step in the development for ERM system standards. Many libraries expressed dissatisfaction with some of the new pricing models for e-journals, especially the Big Deal packages, as libraries were caught between budget reductions, price increases, and complex license agreement terms. Budget and the allocation of funds remained a frequent topic in the literature. With the transition from print to electronic versions, acquisitions staff required more support and new resources. Workflows changed as acquisition units and technical services departments reorganized to accommodate the growth of electronic resources.T his literature of acquisitions review is the continuation of the authors' review covering the literature published from 1996 through 2003. 1 In the previous review, technology and the Internet were the key themes that brought changes to acquisitions, business practices, and communications. For 2004-7, budgets and budget allocation were a continuing concern, with the literature focusing on the complexity and variability of pricing models. The most significant new topic was the management of electronic resources. As patron demand for these resources grew rapidly, a large portion of library materials budgets was spent acquiring them. The literature revealed that acquiring electronic resources was simpler than managing them effectively.To identify the significant acquisitions literature published from 2004 through 2007, searches were made through Library Literature and Information Science Full Text and Library, Information Science and Technology Abstracts with Full Text databases for articles and books. In addition, searches using more specific terms related to acquisitions were made of selected library journals. Citations and abstracts were reviewed for possible inclusion in the review. Searches were limited to scholarly journal articles, conference proceedings, reports, and books in English. Every attempt was made to find literature relating to any aspect of acquisitions; however, the authors concede that some works may have been overlooked. For those articles selected, the papers were retrieved and reviewed in detail. The selected articles then were grouped by topics to establish an outline for presentation. For those papers that bridged more than one topic, an effort was made to put them under the topic that was most prominent. Som...
Objective. Prader-Willi syndrome (PWS) is a complex multisystem genetic disorder in which many cardinal features may have a neurologically based patho-physiology involving both the central and peripheral components of the autonomic nervous system. Autonomic nervous system function was studied noninvasively in a group of subjects with PWS and control subjects to determine whether autonomic nervous system dysfunction exists as part of the PWS. Design/setting. This cross-sectional study was performed in the neurophysiology laboratory at a tertiary care facility. Methods. Evaluation included anthropometric measurements and calculation of a body mass index (BMI). Simultaneous electrocardiography and serial recordings of pulse rate and systolic/diastolic mean arterial blood pressures during orthostatic maneuvers were taken. Pupillary response to the instillation of dilute pilocarpine and measurements of plasma norepinephrine at rest and after standing were also obtained. Results were analyzed using two-tailed t tests, Fisher exact test, analysis of variance, and analysis of covariance adjusting for age, gender, and BMI. Patients. There were 14 subjects with PWS (8 female, 6 male; aged 4 to 40 years, mean age 16 years) and 8 control subjects (4 female, 4 male; aged 5 to 37 years, mean age 19 years). Results. Abnormal findings were obtained only in subjects with PWS. Analysis of covariance adjusting for age, gender, and BMI revealed a trend for subjects with PWS to have lower resting diastolic blood pressure (P < .09) and significantly less change in diastolic blood pressure after standing (P < .02). Subjects with PWS had significantly greater BMI than did control subjects (P < .001), which correlated significantly with all pulse rate measurements where the greater the BMI the higher the pulse rate at rest (r = .25, P < .04) and the lower the pulse rate after arising from lying to standing at both 15 and 30 seconds (r = .17, P < .1; r = .55, P < .08 respectively). Pupillary constriction of 2 mm or more was seen in 7 of 14 subjects with PWS and in no control subjects (P < .004). The 30:15 R-R interval ratio was abnormal in 6 of 14 subjects with PWS and in no control subjects (P < .03). Conclusions. These results suggest that patients with PWS have a detectable underlying autonomic dysfunction characterized principally by diminished parasympathetic nervous system activity.
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