Background:Chlorhexidine varnish (Cervitec- Ivoclar Vivadent- Liechtenstein) is a sustained-release delivery system that can provide protection against white spots and gingivitis, which are common iatrogenic side effects of orthodontic treatment. Chlorhexidine in varnish form does not depend on patient compliance, does not stain teeth or alter taste sensation like the mouth rinse.Materials and Methods:A split-mouth technique was followed in the treatment of 30 patients selected by stringent selection criteria, evaluating a single application of the test varnish on two randomly allotted quadrants along with a placebo on the other two quadrants. Streptococcus mutans counts responsible for white spots and P. gingivalis count [using PCR test] responsible for gingivitis were done at the start of the study, and then 1 and 3 months later.Results:The chlorhexidine varnish reduced the Streptococci mutans count at the end of 1 month, and this reduction was statistically significant. At the end of 3 months, there was no difference in the S. mutans counts between the two groups. There was a statistically significant reduction in the P. gingivalis count at the end of both 1 and 3 months in comparison to the placebo group.Conclusion:Chlorhexidine varnishes are capable of reducing S. mutans and P. gingivalis and gingivitis, thus improving the overall oral health of the patient. The side effects of chlorhexidine mouth rinses are not seen with this varnish. An application schedule of at least once a month is recommended as the effectiveness is reduced comparatively at the end of 3 months.
Aim:
The aim of this study is to review studies evaluating the role of genetics in skeletal class II malocclusion.
Objective:
To assess the scientific evidence associating the role of genes in skeletal class II malocclusion. Materials and Methods: A complete search across the electronic database through PubMed, Cochrane, LILACS, BMC and manual hand search of orthodontic journals were done till May 2019. The keywords for the search included: “Genetics”, “class II malocclusion”, “maxillary prognathism”, “mandibular retrognathism”.
Data Collection and Analysis:
Studies were selected based on PRISMA guidelines.
Results:
Articles were selected based on the inclusion and exclusion criteria. A total of 11 cross-sectional studies satisfied the inclusion criteria and were analyzed for the role of genes in skeletal class II malocclusion. Almost all the studies except for one revealed a positive correlation of genes with skeletal class II malocclusion.
Conclusions:
Out of the 11 studies included, a positive correlation of the genes with the skeletal II malocclusion was found in 10 studies. Genes FGFR2, MSX1, MATN1, MYOH1, ACTN3, GHR, KAT6B, HDAC4, AJUBA were found to be positively linked to skeletal class II malocclusion.
Background:
Osteological examination is a very reliable tool to determine the sex of the individual as the consolidation of the dimorphic characteristics concludes the sex of the individual. This study was performed with lateral cephalograms, which is a vital diagnostic tool for patients undergoing orthodontic treatment. An index was formed, which could be considered as a reliable sex determinant in forensic applications.
Materials and Methods:
This pilot study was performed on samples of the Dravidian population. Two-fifty individuals, whose age ranged between 25 and 40 years, were taken (125 subjects were males and 125 subjects were females). A total of ninety-nine cephalometric variables were compared, subjected to statistical analysis and tested for significance using the
t
-test.
Results:
Out of a total of 99 variables tested only twenty-four variables showed statistical significance. So, these twenty-four variables were then subjected to discriminant function analysis to evaluate the effectiveness of each variable in predicting the sex of an individual Individually, Ramus length (Ramus ln), Condylion to Gnathion (Co-Gn) and ramus height showed the highest sex determining dependability of 78%. On the flipside, lower anterior facial height (LAFH), with 52%, showed the lowest consistency.
Conclusion:
From this study, it is clearly evident that cephalometric landmarks are reliable sex determinants to a good extent. All the statistically significant measurements, but one, showed acceptable percentages of reliability. This means the chosen variables can be used for the Dravidian population to robustly determine the sex of the individuals of interest.
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