The data show that subcutaneous sodium salicylate injections are an effective symptomatic treatment for OA of the thumb. The results provide a basis for further physiological and therapeutic research in this area.

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Context:Prāṇāyāma, the fourth limb of ancient aṣṭāṅga yoga consists of breathing techniques which produce various physiological and psychological effects. Though various types of prāṇāyāma and their effects have been scientifically established, Bhrāmarī prāṇāyāma (Bhr.P) is the one whose effects still remain understated.Aims:The present study was conducted to find the effects of Bhrāmarī prāṇāyāma practice on pulmonary function in healthy adolescents.Study Design:Randomized control trial.Subjects and Methods:90 healthy adolescents including 32 females and 58 males participated in the study. They were randomly divided into Bhr.P group (n = 45) and Control group (n = 45) by a simple lottery method. Pulmonary function test was done at baseline and at end of 12th week using RMS Helios spirometry. Prāṇāyāma group students were trained to do Bhr.P as 3 to 4 breaths/min for 5 min followed by 2 min rest. This was one cycle and in this way, they were instructed to do five cycles each time for 45 minutes five days in a week. Control group students were not allowed to practice any kind of exercise throughout the study period.Statistical Analysis:Student paired and unpaired T tests were used to analyse the intra group and intergroup differences using R statistical software.Results:A significant (P < 0.05) improvement in all pulmonary function parameters; FVC, FEV1, FEV1/FVC ratio, FEF 25%-75% and PEFR was seen in the Bhr.P group than the control group adolescents. Slow vital capacity (SVC) and Maximum Voluntary Volume (MVV) also showed significant improvement in the prāṇāyāma group.Conclusions:Bhrāmarī Prāṇāyāma practice is effective in improving the pulmonary function among the adolescents which could be utilized for further clinical studies.

In recent years, nanotechnology has received extraordinary attention as the demands of today’s modern lifestyle are actively changing every day. The need for a sustainable environment and process is the prerequisite today for any advancement. Nanoparticles and its application have extended its wings into various fields. Researchers across the globe are constantly exploring the applications of NPs, especially those of metallic NPs. Among the metallic NPs, silver NPs has received special attention owing to their excellent physical and chemical properties. Nanobiotechnology has opened avenues for such a sustainable and environment-friendly progress. So, in this review, we have summarized the different methods employed in synthesising AgNPs, with special focus on the biological synthesis. This approach is of importance because of its advantages such as use of nontoxic compounds, inexpensive process, and high stability of products obtained in comparison to the other approaches. Several biomolecules of interest such as microbes and plant extracts that are used for synthesis are discussed in detail. The recent advancements in the environmental application of these biologically synthesised NPs include remediation of heavy metals and sensing, as catalysts in toxic dye degradation, remediation of waste water, and also, as a pesticidal agent for crop protection. Although AgNPs have been used in several sectors of research and industries, relevance to the environment is prominent owing to the impact it makes on the humans and all forms of life on earth.

In recent decades, research in nanomaterial specific to biodegradation has gained attraction owing to its physicochemical characteristics. Biodegradation is the main strategy used in the management of wastes. The role of nanoparticles helps in controlling the biodegradation rate. The biodegradation might not be quite effective in certain cases like high chemical deposition, due to its toxic nature towards microorganisms. The conventional strategies demonstrated a limited use of nature source, and this could be overcome through microbes and enzyme-based biodegradation. Nanoparticles have improved the biodegradation rate through low-density polyethylene development, thereby corrupting microbes. Thus, a major problem is confronted. Though innovation in science had a great impact in everyone’s life, it also has a negative impact through the increased use of toxic materials. Recent development and use of biodegradable nano-based compounds have led to many secured forms of nanomedicines. In this review, we would discuss the more recent findings of nanoparticles related to biodegradation applications and elaborate how their characteristics could influence in various biomedical applications.