This paper aims to characterize dynamics of a fire in the Large-Scale Demonstrator Malveira Fire Test, a full-scale fire experiment carried out in a disused industrial building in Portugal. The Malveira Fire Test is the second stage in the series of full-scale experimental programmes developed for the Real Fires for the Safe Design of Tall Buildings project at the University of Edinburgh. This experiment is intended to act as a real-building demonstration of fire dynamics in large open-floor plan compartments and has as objective to provide a data set to contrast methodologies aiming at design fire inputs representative of real fire dynamics in compartments typical of tall buildings. The Malveira Fire Test showed three distinct fire behaviour modes characterised by the ratio between the velocities of the fire front (") and the burnout front (#$
The adjustment of the location of the anastomosis of the LVAD outflow cannula as well as its angle of incidence plays a significant role in the level of thromboembolisms. By proper adjustment in this CFD study of a synthetic model of an aortic arch bed, we found that nearly a 50% reduction in cerebral embolism could be achieved for a configuration consisting of a shallow angle of implantation over a baseline normal incidence of the LVAD cannula. Within the limitations of our model, we have established that the LVAD implantation geometry is an important factor and should be taken into consideration when implanting an LVAD. It is possible that other parameters such as distance of the LVAD outflow cannula to the root of the IA could affect the thrombi embolisation probabilities. However, the results of this study suggest that the risk of stroke may be significantly reduced by as much as 50% by tailoring the VAD implantation by a simple surgical manoeuvre. The results of this line of research may ultimately lead to techniques that can be used to estimate the optimal LVAD configuration in a patient-specific manner by pre-operative imaging.
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