The clinical results of the studies point to the positive effects of radiofrequency on the reduction in adipose tissue; however, the low methodological make this topic still debatable, requiring more controlled studies.

Background Non-invasive vagus nerve stimulation (nVNS) is a proven treatment for cluster headache and migraine. Several possible mechanisms of action by which nVNS mitigates headache have been identified. Methods We conducted a narrative review of recent scientific and clinical research into nVNS for headache, including findings from mechanistic studies and their possible relationships to the clinical effects of nVNS. Results Findings from animal and human studies have provided possible mechanistic explanations for nVNS efficacy in headache involving four core areas: Autonomic nervous system functions; cortical spreading depression inhibition; neurotransmitter regulation; and nociceptive modulation. We discuss how overlap and interplay among these areas may underlie the utility of nVNS in the context of clinical evidence supporting its safety and efficacy as acute and preventive therapy for both cluster headache and migraine. Possible future nVNS applications are also discussed. Conclusion Significant progress over the past several years has yielded valuable mechanistic and clinical evidence that, combined with the excellent safety and tolerability profile of nVNS, suggests that it should be considered a first-line treatment for both acute and preventive treatment of cluster headache, an effective option for acute treatment of migraine, and a highly relevant, practical option for migraine prevention.

Background: Abdominal adiposity is a cardiovascular risk factor; it is assumed that the combination of radiofrequency and physical exercise may decrease this excess of adipose tissue. Purpose: To analyze the effect of four intervention sessions on abdominal adipose tissue. Methodology: The study analyzes the effect of four sessions of aerobic exercise combined with radiofrequency. Participants were 28 healthy female volunteers, aged 18-28 years, randomly assigned to an experimental group and a placebo group. They were characterized by a sociodemographic questionnaire, the International Physical Activity Questionnaire and the Food Frequency Questionnaire. The groups performed four sessions of abdominal radiofrequency followed by moderate aerobic exercise, assessing body mass, body mass index, fat mass, waist circumference, waist/height ratio, subcutaneous adipose thickness, and horizontal abdominal adipose fold at the first and fourth sessions. In the experimental group, a percentage of potency was used that allowed to maintain the temperature between 40°C and 42°C to the epidermis. In the placebo group, the power of the radiofrequency was 0 W. To compare results, Student's t test was used for a significance level of 0.05. Results: There was a statistically significant decrease in waist circumference, abdominal subcutaneous adipose thickness, and horizontal abdominal fold in the experimental group compared to the placebo group (P < 0.05). Conclusion: Combined exercise intervention with radiofrequency has been shown to be effective in reducing abdominal adiposity.

Abstract Brazil accounts for a large percentage of the world’s citrus production, with ‘Tahiti’ acid lime tree standing out among several cultivated species. However, its cultivation is supported by a very narrow genetic base, being composed of few scion and rootstock options. In this way, the aim of this study was to evaluate the vegetative development and production of twelve ‘Tahiti’ acid lime clones on two rootstocks. The experiment was carried out at Fazenda José Guarete, municipality of São Mateus – ES. A randomized block design was used in the split plot scheme, with plot consisting of two rootstocks and subplot of the twelve ‘Tahiti’ acid lime clones. Traits evaluated were: vegetative development, production and productive efficiency, internal and external quality of fruits. Bello Fruit, Iconha, BRS Passos, Itarana, Persian 58, CNPMF 5059 and Elédio clones were superior in terms of production, vegetative traits and fruit quality. ‘Swingle’ citrumelo rootstock showed higher values for vegetative traits compared to ‘Riverside’ citrandarin. The clone and rootstock combinations that provided better agronomic performance in this study were BRS Passos, Bello Fruit, Elédio and Iconha grafted on ‘Swingle’ citrumelo and CNPMF 5059, Iconha and Elédio grafted on ‘Riverside’ citrandarin.