HighlightsLMD was used to investigate 3-D molecular heterogeneity in ovarian cancer tissue Diverse molecular profiles were identified from 3-D spatially separated samples Molecular heterogeneity impacts HGSOC prognostic sub-type assignment Proteomic heterogeneity analysis web portal deployed at www. lmdomics.org
An ocular toxic reaction presenting as conjunctivitis or keratitis develops in a significant number of patients who are treated with high‐dose cytosine arabinoside (ara‐C). Although eye drops containing glucocorticoid reportedly decrease the incidence, they do not totally eliminate this side effect. In comparing this technique with artificial tears, both were found to be equally effective. The primary mechanism by which eye drops decrease ocular toxic reactions associated with high‐dose ara‐C is presumably due to dilution of intraocular concentrations of ara‐C.
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