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HA, IM, and MC were predictors of malignancy in Bethesda III nodules. In addition, the negative predictive value for any of these three criteria was high; a nodule that lacks all of these three criteria is thus unlikely to be malignant.

Background: The pathogenesis of seroma formation following axillary dissection continues to be poorly understood, although it seems that the greater the surgical disruption of the axilla, the higher the incidence of seroma and lymphoedema. We have previously described the laminated, three-dimensional structure of the clavipectoral fascia (CPF) that is evident during axillary ultrasonography and dissection . We propose that reconstituting the CPF reduces dead space, partially restores pressure gradients and facilitates collateralization to improve lymphatic flow, thereby reducing the incidence of seromas. Herewith, is a description of our technique for reconstitution of the CPF and our experience thus far. Method: Technique: Following mastectomy or breast conservation surgery, the lateral border of pectoralis major is defined. Here, the medial, anterior laminae of the CPF are identified but not incised. Once the anterior extent of the CPF is displayed, a longitudinal incision is made through the midpoint of the CPF to access the axillary contents. If there is a substantial axillary tail, then the CPF is incised along the perimeter of the tail to include intra-mammary lymph nodes. A loose areolar tissue plane is encountered; the edges of the CPF are grasped and elevated and this areolar tissue plane developed by blunt and sharp dissection. Medially, this loose areolar tissue plane leads directly to a posterior gutter, and the long thoracic nerve on serratus anterior is identified and preserved. Superiorly, a deeper lamina of the CPF along the inferior border of the axillary vein has to be incised to find the thoracodorsal nerve. Identification of the intercostobrachial nerves is standard, as is the lateral dissection. Identification of the long thoracic nerve and thoracodorsal bundle results in definition of a vertical sheet, ‘the interneural tissue’. This can be grasped between the thumb and index finger and is excised en bloc. This tissue contains fat, lymph nodes and lymphatic vessels and is lined by thin fascial layers that we consider related to the CPF3. At this stage, the anterior laminae of the CPF and axilla are carefully palpated for any residual nodes. After haemostasis, the CPF is reconstituted with a running, absorbable ‘lymphostatic’ suture. No drain is placed in the axilla. Results: Between 2012 – 2015, 64 patients have undergone axillary dissection with reconstitution of the CPF in our unit.. The average age was 54 years (range 29-87 years). An average of 12 nodes were procured (range 2-26 nodes). Only 5 women (8%) required seroma aspiration. Conclusion: We have dispensed with axillary drains in those who have had reconstitution of the CPF and only a minority of our patients required axillary seroma aspiration. We believe this technique should be given consideration to decrease the use of drains following axillary dissection. Citation Format: Meredith IC, Popadich A, Mouat CH, Barrett K, King B. Endofascial axillary lymphadenectomy – Towards a drainless protocol. [abstract]. In: Proceedings of the Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2015 Dec 8-12; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2016;76(4 Suppl):Abstract nr P2-12-03.

Purpose  Oesophagectomy is associated with considerable morbidity, mortality and poor survival of patients who have undergone oesophagectomy for oesophageal carcinoma. Numerous studies have examined the impact of hospital volume on early mortality, most demonstrating a strong inverse relationship between operative mortality and hospital case volume. This study looks at the morbidity, mortality and 2‐year survival of patients following oesophagectomy at Dunedin hospital, a low volume centre, and comparing it to high volume centres. Methods  A retrospective analysis of all patients who had elective oesophagectomy between 1995 and 2004. Otago Surgical Audit database, patient management system database (OraCare) as well as operating theatre database were used. Results  40 patients were identified, which had either transhiatal or Ivor‐Lewis procedure. 50% had pre‐op chemotherapy and 33% pre‐op radiotherapy. 65% had adenocarcinoma, 10% squamous cell carcinoma and 15% had Barrett’s with severe dysplasia. The mortality at Dunedin was 5%. Complications were: respiratory 37.5%, leak 10%, wound 22.5%, oesophageal stricture 2.5% and chylothorax 2.5%. Median length of stay was 15 days (11–94). Median survival of patients with oesophageal carcinoma was 26 months. Median survival of node negative patients was 34.5 months and node positive patients 14 months. Conclusion  Prognosis for patients with node‐positive disease continues to be poor despite oesophagectomy. The complication rates and in‐hospital mortality at Dunedin are similar to high volume centres. This study shows that patients undergoing oesophagectomy at low volume hospital do not have increased risk of operative mortality.