Watchful observation or early therapeutic intervention with established cardioprotective medications may be necessary for patients with malignant lymphoma and preserved LVEF but with abnormal GLS.

The prognosis of patients with cancer has improved due to an early diagnosis of cancer and advances in cancer treatment. There are emerging reports on cardiotoxicity in cancer treatment and on cardiovascular disease in cancer patients, from which cardiovascular disease has been recognized as a common cause of death among cancer survivors. This situation has led to the need for a medical system in which oncologists and cardiologists work together to treat patients. With the growing importance of onco-cardiology, the role of echocardiography in cancer care is rapidly expanding, but at present, the practice of echocardiography in clinical settings varies from institution to institution, and is empirical with no established systematic guidance. In view of these circumstances, we thought that brief guidance for clinical application was necessary and have therefore developed this guidance, although evidence in this field is still insufficient.

A patient with lung cancer was administrated osimertinib. She developed symptomatic heart failure due to Takotsubo cardiomyopathy (TC). As her condition improved after discontinuing osimertinib, TC was thought to be caused by osimertinib. Reoccurrence of TC was seen after readministrating half dose of osimertinib.

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I n a patient with sarcomatoid carcinoma of left main bronchus, a computed tomography scan revealed an abnormal mass in the apex of the left ventricle (LV) (A). Echocardiography showed a well-defined hyperechoic mass in the same region, wall motion was reduced in the apex and posterolateral wall, and there was thinning of the posterior wall (Online Videos 1 and 2), suggesting old myocardial infarction and that the mass was due to thrombus.Then, fluorodeoxyglucose-positron emission tomography (FDG-PET) was performed. Strong accumulation was detected inside the apex, extending into the apical and lateral wall (B), indicating high metabolic activity, which is consistent with tumor invasion. Therefore, the mass was diagnosed as a large intracardiac metastasis.