We present our experience at the University of Illinois at Chicago (UIC) in deep brain stimulation (DBS) of the subthalamic nucleus (STN), describing our surgical technique, and reporting our clinical results, and morbidities. Twenty patients with advanced Parkinson’s disease (PD) who underwent bilateral STN-DBS were studied. Patients were assessed preoperatively and followed up for one year using the Unified Parkinson’s Disease Rating Scale (UPDRS) in “on” and “off” medication and “on” and “off” stimulation conditions. At one-year follow-up, we calculated significant improvement in all the motor aspects of PD (UPDRS III) and in activities of daily living (UPDRS II) in the “off” medication state. The “off” medication UPDRS improved by 49.3%, tremors improved by 81.6%, rigidity improved by 50.0%, and bradykinesia improved by 39.3%. The “off” medication UPDRS II scores improved by 73.8%. The Levodopa equivalent daily dose was reduced by 54.1%. The UPDRS IVa score (dyskinesia) was reduced by 65.1%. The UPDRS IVb score (motor fluctuation) was reduced by 48.6%. Deep brain stimulation of the STN improves the cardinal motor manifestations of the idiopathic PD. It also improves activities of daily living, and reduces medication-induced complications.
Using multiplanar image-guided trajectory planning and a small biopsy needle decreases the incidence of post-biopsy hemorrhage. Neurologically intact patients with no hemorrhage in post-biopsy CT scan could safely be discharged home at the same operative day.
Introduction: The anterior communicating artery complex consists of two anterior cerebral arteries (ACA), the anterior communicating artery (AComA) and the recurrent arteries of Heubner. ACA is divided into the three segments; A1 originating from the internal carotid artery, A2 extending from AComA and A3 also known as the pericallosal artery. The anatomical variations of the ACoA complex are not adequately discussed. The aim of this study is to detect the anatomical variations in the ACoA complex in patients that don’t have any intracranial vascular pathology.
Aims: The present study determines the anatomical Variations of the anterior communicating artery complex.
Patients and Methods: The study group consists of 70 subjects, using Digital Subtraction Angiography and Computed Tomography Angiography to visualize the vascular anatomy.
Results: About 14.29% (10 patients) Aplastic ACoA, 7.14% (5 patients) have unilateral A1 ACA segment hypoplasia, 2.86% (2 patients) have unilateral A1 ACA segment aplasia.
Conclusion: The most common anatomical variant is Aplastic ACoA.
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