Background Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently constitutes the leading and overwhelming health issue worldwide. In comparison with adults, children present milder symptoms, with most having an asymptomatic course. We hypothesized that COVID-19 infection has a negative impact on the continuation of chemotherapy and increases nonrelapse mortality. Material and methods This study was performed to assess the course of SARS-CoV-2 among children with hematological or oncological malignancies and its impact on cancer therapy. Records of SARS-CoV-2 infection in 155 children with malignancies from 14 Polish centers for pediatric hematology and oncology were collected and analyzed. Results SARS-CoV-2 replication was observed in 155 patients. Forty-nine patients were symptomatic, with the following being the most common manifestations: fever (31 patients), gastrointestinal symptoms (10), coryza (13), cough (13) and headache (8). In children who were retested, the median time of a positive PCR result was 16 days (range 1–70 days), but 12.7% of patients were positive beyond day + 20. The length of viral PCR positivity correlated with the absolute neutrophil count at diagnosis. Seventy-six patients did not undergo further SARS-CoV-2 testing and were considered convalescents after completion of isolation. Antibiotic therapy was administered in 15 children, remdesivir in 6, convalescent plasma in 4, oxygen therapy in 3 (1—mechanical ventilation), steroids in 2, intravenous immunoglobulins in 2, and heparin in 4. Eighty patients were treated with chemotherapy within 30 days after SARS-CoV-2 infection diagnosis or were diagnosed with SARS-CoV-2 infection during 30 days of chemotherapy administration. Respiratory symptoms associated with COVID-19 and associated with oxygen therapy were present in 4 patients in the study population, and four deaths were recorded (2 due to COVID-19 and 2 due to progressive malignancy). The probability of 100-day overall survival was 97.3% (95% CI 92.9–99%). Delay in the next chemotherapy cycle occurred in 91 of 156 cases, with a median of 14 days (range 2–105 days). Conclusions For the majority of pediatric cancer patients, SARS-CoV-2 infection does not result in a severe, life-threatening course. Our data show that interruptions in therapy are common and can result in suboptimal therapy.
Samoocena stylu życia i profilaktyka raka gruczołu piersiowego na przykładzie studentek wybranych uczelni trójmiastaThe self-assessment of lifestyle and prevention of breast cancer on the example of female students from selected high schools in Tricity Streszczenie Wstęp. Rak gruczołu piersiowego jest jedynym z najczęściej wykrywanych nowotworów u kobiet w Polsce i na świecie. Rozpoznanie choroby w początkowym stadium rozwoju zwiększa szanse na wyleczenie chorego. Przestrzeganie zasad zdrowego stylu życia oraz udział w badaniu mammograficznym i samobadaniu piersi odgrywa znaczącą rolę w profilaktyce raka piersi.Cel. Celem pracy była analiza zachowań zdrowotnych studentek trójmiejskich uczelni w odniesieniu do profilaktyki raka gruczołu piersiowego.Materiał i metody. Materiał stanowi 168 studentek Gdańskiego Uniwersytet Medycznego, Uniwersytetu Gdań-skiego, Politechniki Gdańskiej oraz Wyższej Szkoły Humanistycznej w Gdańsku. Badania przeprowadzono w okresie od marca do czerwca 2010 roku. W realizacji pracy posłu-żono się metodą sondażu diagnostycznego, a do wyliczenia zależności między zmiennymi wykorzystano współczynnik korelacji liniowej Pearsona.Wyniki. Wyniki badań wskazują, że poziom wiedzy na temat zachowań zdrowotnych oraz wykonywania samobadania piersi i mammografii w grupie studentek wybranych gdańskich uczelni jest zadawalający. Pomimo posiadanej wiedzy studentki nie wykonują samobadania piersi, a ich dieta nie jest dostatecznie zbilansowana. Uzyskane wyniki wskazują, że temat stosowania alkoholu wśród kobiet nie może być bagatelizowany.Wnioski. Brak nawyku samobadania piersi wśród studentek gdańskich uczelni jest potwierdzeniem nieskuteczności podejmowanych działań edukacyjnych co powinno zostać zauważone przez pracowników medycznych, a w tym pielęgniarki i położne. AbstractIntroduction. Breast cancer is one of the most frequently diagnosed female malignancies in Poland and worldwide. Detection of the disease at its early stages increases the probability of recovery. Obeying the rules of healthy lifestyle, participation in mammographic screening, and selfexamination of breasts play vital role in breast cancer prevention.Aim. To analyze the health-related behaviors regarding breast cancer prevention among the female students of higher education institutions from Tricity.Material and methods. The study included 168 female students of the Medical University of Gdansk, University of Gdansk, Gdansk University of Technology, and Gdansk Higher School of Humanities, and was conducted between March and June 2010. We used the method of diagnostic survey, and relationships between studied variables were determined on the basis of Pearson's coefficient of linear correlation.Results. Our study revealed that the group of students from selected Gdansk higher education institutions present satisfactory level of knowledge with regards to health-related behaviors, self-examination of breast, and mammographic screening. Despite possessed knowledge, our students do not self-examine their breasts, and their diet is not suf...
Work accidents are a subject of particularly tight control, and craniofacial injuries belong to the most difficult types of trauma in terms of their pre-hospital management. The aim of this paper is to present the case of a patient who experienced craniofacial injury during a work accident. Analysis of the case history showed that due to specific type of injuries, this patient required complex surgical treatment and multi disciplinary consultations. Due to long-term incapacity for work, craniofacial injuries constitute an organizational and economic challenge.
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