We present a new measurement of the inclusive forward-backward tt production asymmetry and its rapidity and mass dependence. The measurements are performed with data corresponding to an integrated luminosity of 5.3 fb −1 of pp collisions at √ s = 1.96 TeV, recorded with the CDF II Detector at the Fermilab Tevatron. Significant inclusive asymmetries are observed in both the laboratory frame and the tt rest frame, and in both cases are found to be consistent with CP conservation under interchange of t andt. In the tt rest frame, the asymmetry is observed to increase with the tt rapidity difference, ∆y, and with the invariant mass M tt of the tt system. Fully corrected parton-level asymmetries are derived in two regions of each variable, and the asymmetry is found to be most significant at large ∆y and M tt . For M tt ≥ 450 GeV/c 2 , the parton-level asymmetry in the tt rest frame is A tt = 0.475 ± 0.114 compared to a next-to-leading order QCD prediction of 0.088 ± 0.013.

No abstract

The incidence of renal cell carcinoma (RCC) is increasing worldwide, and its prevalence is particularly high in some parts of Central Europe. Here we undertake whole-genome and transcriptome sequencing of clear cell RCC (ccRCC), the most common form of the disease, in patients from four different European countries with contrasting disease incidence to explore the underlying genomic architecture of RCC. Our findings support previous reports on frequent aberrations in the epigenetic machinery and PI3K/mTOR signalling, and uncover novel pathways and genes affected by recurrent mutations and abnormal transcriptome patterns including focal adhesion, components of extracellular matrix (ECM) and genes encoding FAT cadherins. Furthermore, a large majority of patients from Romania have an unexpected high frequency of A:T4T:A transversions, consistent with exposure to aristolochic acid (AA). These results show that the processes underlying ccRCC tumorigenesis may vary in different populations and suggest that AA may be an important ccRCC carcinogen in Romania, a finding with major public health implications.

We report on a search for new particles in the diphoton channel using a data sample of pp collisions at √ s = 1.96 TeV collected by the CDF II detector at the Fermilab Tevatron, with an integrated luminosity of 5.4 fb −1 . The diphoton invariant mass spectrum of the data agrees well with the standard model expectation. We set upper limits on the production cross section times branching ratio for the Randall-Sundrum graviton, as a function of diphoton mass. We subsequently derive lower limits on the graviton mass of 459 GeV/c 2 and 963 GeV/c 2 , at the 95% confidence level, for coupling parameters (k/M P l ) of 0.01 and 0.1 respectively.

No abstract