Magnesium deficiency in patients with ischemic heart disease with and without acute myocardial infarction uncovered by an intravenous loading test

Magnesium for the prevention and treatment of cardiovascular disease

“…Unsurprisingly, when the patients with ischaemic heart disease were subgrouped according to long-term diuretic treatment, the patients receiving long-term diuretic treatment had a 39% retention of magnesium (11.6 mmol/L (28.2 mg/dL)) compared with a 29% retention (8.7 mmol/L (21.1 mg/dL)). This study indicates that patients with ischaemic heart disease may be severely magnesium deficient and that long-term diuretic treatment may contribute to this deficiency 104. The beneficial effect of intravenous magnesium treatment in acute myocardial infarction has also been demonstrated in regards to reducing both mortality and early cardiac insufficiency.…”

Magnesium for the prevention and treatment of cardiovascular disease

“…Unsurprisingly, when the patients with ischaemic heart disease were subgrouped according to long-term diuretic treatment, the patients receiving long-term diuretic treatment had a 39% retention of magnesium (11.6 mmol/L (28.2 mg/dL)) compared with a 29% retention (8.7 mmol/L (21.1 mg/dL)). This study indicates that patients with ischaemic heart disease may be severely magnesium deficient and that long-term diuretic treatment may contribute to this deficiency 104. The beneficial effect of intravenous magnesium treatment in acute myocardial infarction has also been demonstrated in regards to reducing both mortality and early cardiac insufficiency.…”

Magnesium Metabolism and Clinical Characteristics of Patients With Chronic Ischemic Heart Disease

“…Степень задержки магния у больных ИБС с признаками его дефицита (более 70,0%) превосходила соответствующий показатель у пациентов с нормальным обменом катиона и у здоровых, что позволяет рассматривать ее как пороговый уровень для верификации диагноза системного ДМ. Полученные результаты отличаются от критериев интерпретации нагрузочного теста по H. S. Rasmussen [12], что можно объяснить коррекцией доз сульфата магния и модификацией режима его введения и выполнением исследования у лиц, проживающих, как указывалось, в магний-дефицитном регионе. В ходе пробы с дозированной физической нагрузкой проведено уточнение взаимоотношений катионов у больных ИБС.…”

Can one really measure magnesium deficiency using the short‐term magnesium loading test?

“…Groups 2 and 3 were also normomagnesemic regarding the mean value, but at the lower limit of the Mg reference value in our laboratory (1.15–0.75 mmol L –1 ). Patients after renal transplantation were outpatients in whom Mg depletion might have developed due to renal Mg wasting [20] related to a defective renal tubular system because of ischemia and the nephrotoxicity of various drugs especially ciclosporine [7, 10, 16]. The loading‐test was applied to answer the question of whether there is magnesium deficiency or not.…”

Magnesium for the prevention and treatment of cardiovascular disease

“…Unsurprisingly, when the patients with ischaemic heart disease were subgrouped according to long-term diuretic treatment, the patients receiving long-term diuretic treatment had a 39% retention of magnesium (11.6 mmol/L (28.2 mg/dL)) compared with a 29% retention (8.7 mmol/L (21.1 mg/dL)). This study indicates that patients with ischaemic heart disease may be severely magnesium deficient and that long-term diuretic treatment may contribute to this deficiency 104. The beneficial effect of intravenous magnesium treatment in acute myocardial infarction has also been demonstrated in regards to reducing both mortality and early cardiac insufficiency.…”

Magnesium Metabolism and Clinical Characteristics of Patients With Chronic Ischemic Heart Disease

“…Степень задержки магния у больных ИБС с признаками его дефицита (более 70,0%) превосходила соответствующий показатель у пациентов с нормальным обменом катиона и у здоровых, что позволяет рассматривать ее как пороговый уровень для верификации диагноза системного ДМ. Полученные результаты отличаются от критериев интерпретации нагрузочного теста по H. S. Rasmussen [12], что можно объяснить коррекцией доз сульфата магния и модификацией режима его введения и выполнением исследования у лиц, проживающих, как указывалось, в магний-дефицитном регионе. В ходе пробы с дозированной физической нагрузкой проведено уточнение взаимоотношений катионов у больных ИБС.…”

Can one really measure magnesium deficiency using the short‐term magnesium loading test?

“…Groups 2 and 3 were also normomagnesemic regarding the mean value, but at the lower limit of the Mg reference value in our laboratory (1.15–0.75 mmol L –1 ). Patients after renal transplantation were outpatients in whom Mg depletion might have developed due to renal Mg wasting [20] related to a defective renal tubular system because of ischemia and the nephrotoxicity of various drugs especially ciclosporine [7, 10, 16]. The loading‐test was applied to answer the question of whether there is magnesium deficiency or not.…”

Magnesium for the prevention and treatment of cardiovascular disease

“…Unsurprisingly, when the patients with ischaemic heart disease were subgrouped according to long-term diuretic treatment, the patients receiving long-term diuretic treatment had a 39% retention of magnesium (11.6 mmol/L (28.2 mg/dL)) compared with a 29% retention (8.7 mmol/L (21.1 mg/dL)). This study indicates that patients with ischaemic heart disease may be severely magnesium deficient and that long-term diuretic treatment may contribute to this deficiency 104. The beneficial effect of intravenous magnesium treatment in acute myocardial infarction has also been demonstrated in regards to reducing both mortality and early cardiac insufficiency.…”

Magnesium Metabolism and Clinical Characteristics of Patients With Chronic Ischemic Heart Disease

“…Степень задержки магния у больных ИБС с признаками его дефицита (более 70,0%) превосходила соответствующий показатель у пациентов с нормальным обменом катиона и у здоровых, что позволяет рассматривать ее как пороговый уровень для верификации диагноза системного ДМ. Полученные результаты отличаются от критериев интерпретации нагрузочного теста по H. S. Rasmussen [12], что можно объяснить коррекцией доз сульфата магния и модификацией режима его введения и выполнением исследования у лиц, проживающих, как указывалось, в магний-дефицитном регионе. В ходе пробы с дозированной физической нагрузкой проведено уточнение взаимоотношений катионов у больных ИБС.…”

Can one really measure magnesium deficiency using the short‐term magnesium loading test?

“…Groups 2 and 3 were also normomagnesemic regarding the mean value, but at the lower limit of the Mg reference value in our laboratory (1.15–0.75 mmol L –1 ). Patients after renal transplantation were outpatients in whom Mg depletion might have developed due to renal Mg wasting [20] related to a defective renal tubular system because of ischemia and the nephrotoxicity of various drugs especially ciclosporine [7, 10, 16]. The loading‐test was applied to answer the question of whether there is magnesium deficiency or not.…”