Reliability of the Routine Cytological Diagnosis in Bladder Cancer

Making Cytological Diagnoses on Digital Images Using the iPath Network

“…The diagnostic difficulties and the high interobserver variability in urinary cytology have already been well perceived in previous studies [13,18,39]. Our previous online quiz with 246 participants showed that only 34% of the low-grade and 76% of the high-grade urothelial neoplastic lesions (G3) were concordantly assessed by the participants and that the rate of false diagnoses was also relatively high, even among experienced cytologists [18].…”

Making Cytological Diagnoses on Digital Images Using the iPath Network

“…The diagnostic difficulties and the high interobserver variability in urinary cytology have already been well perceived in previous studies [13,18,39]. Our previous online quiz with 246 participants showed that only 34% of the low-grade and 76% of the high-grade urothelial neoplastic lesions (G3) were concordantly assessed by the participants and that the rate of false diagnoses was also relatively high, even among experienced cytologists [18].…”

Urine cytology as seen in Uyo, Nigeria: How relevant is it to medical practice?

“…in their study observed that negative for malignant cell smears does not exclude malignancy. [ 16 ] Hence, in situations where there is a strong suspicion of bladder cancer, other modalities should be used.…”

Is It Necessary to Perform Urine Cytology in Screening Patients with Haematuria?

“…A negative cytology, however, does not rule out the presence of transitional cell carcinoma due to lack of overall sensitivity, especially in lower–grade tumours [2]. Suspicious cytology, also called indeterminate or atypical, may suggest malignancy, but may also arise due to a variety of non–neoplastic conditions [4]. In addition, urine is an inhospitable medium for desquamated urothelial cells, which leads to difficulty in assessing cytology specimens.…”

Making Cytological Diagnoses on Digital Images Using the iPath Network

“…The diagnostic difficulties and the high interobserver variability in urinary cytology have already been well perceived in previous studies [13,18,39]. Our previous online quiz with 246 participants showed that only 34% of the low-grade and 76% of the high-grade urothelial neoplastic lesions (G3) were concordantly assessed by the participants and that the rate of false diagnoses was also relatively high, even among experienced cytologists [18].…”

Urine cytology as seen in Uyo, Nigeria: How relevant is it to medical practice?

“…in their study observed that negative for malignant cell smears does not exclude malignancy. [ 16 ] Hence, in situations where there is a strong suspicion of bladder cancer, other modalities should be used.…”

Is It Necessary to Perform Urine Cytology in Screening Patients with Haematuria?

“…A negative cytology, however, does not rule out the presence of transitional cell carcinoma due to lack of overall sensitivity, especially in lower–grade tumours [2]. Suspicious cytology, also called indeterminate or atypical, may suggest malignancy, but may also arise due to a variety of non–neoplastic conditions [4]. In addition, urine is an inhospitable medium for desquamated urothelial cells, which leads to difficulty in assessing cytology specimens.…”

Making Cytological Diagnoses on Digital Images Using the iPath Network

“…The diagnostic difficulties and the high interobserver variability in urinary cytology have already been well perceived in previous studies [13,18,39]. Our previous online quiz with 246 participants showed that only 34% of the low-grade and 76% of the high-grade urothelial neoplastic lesions (G3) were concordantly assessed by the participants and that the rate of false diagnoses was also relatively high, even among experienced cytologists [18].…”

Urine cytology as seen in Uyo, Nigeria: How relevant is it to medical practice?

“…in their study observed that negative for malignant cell smears does not exclude malignancy. [ 16 ] Hence, in situations where there is a strong suspicion of bladder cancer, other modalities should be used.…”

Is It Necessary to Perform Urine Cytology in Screening Patients with Haematuria?

“…A negative cytology, however, does not rule out the presence of transitional cell carcinoma due to lack of overall sensitivity, especially in lower–grade tumours [2]. Suspicious cytology, also called indeterminate or atypical, may suggest malignancy, but may also arise due to a variety of non–neoplastic conditions [4]. In addition, urine is an inhospitable medium for desquamated urothelial cells, which leads to difficulty in assessing cytology specimens.…”