Origin and destination of globules and irregular masses in the gonadotropin cells from the pituitary of the African catfish, Clarias gariepinus: a morphological study

Cell Type-Specific Sorting of Neuropeptides: A Mechanism to Modulate Peptide Composition of Large Dense-Core Vesicles

“…For example, the gonadotropin hormone (GTH)-secreting cells of the African catfish Claria gariepinus contain granules with a LEG-like morphology and a condensed protein content. Recent immunoelectron microscopy revealed that these bodies specifically contain the ␤-subunit of GTH, whereas the LDCV contain both ␣and ␤-GTH (Sharp-Baker et al, 1995). Moreover, it was shown that the ␤-GTH-rich granules are post-Golgi compartments, which obtain lysosomal enzymes and degrade their content.…”

Cell Type-Specific Sorting of Neuropeptides: A Mechanism to Modulate Peptide Composition of Large Dense-Core Vesicles

“…For example, the gonadotropin hormone (GTH)-secreting cells of the African catfish Claria gariepinus contain granules with a LEG-like morphology and a condensed protein content. Recent immunoelectron microscopy revealed that these bodies specifically contain the ␤-subunit of GTH, whereas the LDCV contain both ␣and ␤-GTH (Sharp-Baker et al, 1995). Moreover, it was shown that the ␤-GTH-rich granules are post-Golgi compartments, which obtain lysosomal enzymes and degrade their content.…”

Cell Type-Specific Sorting of Neuropeptides: A Mechanism to Modulate Peptide Composition of Large Dense-Core Vesicles

“…For example, the gonadotropin hormone (GTH)-secreting cells of the African catfish Claria gariepinus contain granules with a LEG-like morphology and a condensed protein content. Recent immunoelectron microscopy revealed that these bodies specifically contain the ␤-subunit of GTH, whereas the LDCV contain both ␣and ␤-GTH (Sharp-Baker et al, 1995). Moreover, it was shown that the ␤-GTH-rich granules are post-Golgi compartments, which obtain lysosomal enzymes and degrade their content.…”

Cell Type-Specific Sorting of Neuropeptides: A Mechanism to Modulate Peptide Composition of Large Dense-Core Vesicles

“…For example, the gonadotropin hormone (GTH)-secreting cells of the African catfish Claria gariepinus contain granules with a LEG-like morphology and a condensed protein content. Recent immunoelectron microscopy revealed that these bodies specifically contain the ␤-subunit of GTH, whereas the LDCV contain both ␣and ␤-GTH (Sharp-Baker et al, 1995). Moreover, it was shown that the ␤-GTH-rich granules are post-Golgi compartments, which obtain lysosomal enzymes and degrade their content.…”