One in four people may develop symptomatic hip osteoarthritis in his or her lifetime

Abstract

Summary Objective To estimate the lifetime risk of symptomatic hip osteoarthritis (OA). Design We analyzed data from the Johnston County Osteoarthritis Project (a longitudinal population-based study of OA in North Carolina, United States [n=3,068]). The weighted baseline sample comprised 18% blacks and 54% women, and the mean age was 63 years (range=45-93). Symptomatic hip OA was defined as a Kellgren-Lawrence (K-L) radiographic score of ≥2 (anterior-posterior pelvis x-rays) and pain, aching or stiffness on most days, or groin pain, in the same hip. Lifetime risk, defined as the proportion who developed symptomatic hip OA in at least one hip by age 85, among people who live to age 85, was modeled using logistic regression with repeated measures (through generalized estimating equations). Results Lifetime risk of symptomatic hip OA was 25.3% (95% confidence interval [CI] = 21.3–29.3). Lifetime risk was similar by sex, race, highest educational attainment, and hip injury history. We studied lifetime risk by body mass index (BMI) in three forms: at age 18; at baseline and follow-up; and at age 18, baseline and follow-up and found no differences in estimates. Conclusion The burden of symptomatic hip OA is substantial with one in four people developing this condition by age 85. The similar race-specific estimates suggest that racial disparities in total hip replacements are not attributable to differences in disease occurrence. Despite increasing evidence that obesity predicts an increased risk of both hip OA and joint replacement, we found no association between BMI and lifetime risk.

Osteoarthritis of the hip: are degenerative tears of the acetabular labrum predictable from features on hip radiographs?

“…The demographic data of the present study demonstrates a female subject predominance, a finding that parallels the existing literature showing the increased female prevalence of arthritic patients (12–14). While there were more female participants, there was no statistical difference in the measured radiographic features between women and men ( P > 0.05).…”

Osteoarthritis of the hip: are degenerative tears of the acetabular labrum predictable from features on hip radiographs?

“…The demographic data of the present study demonstrates a female subject predominance, a finding that parallels the existing literature showing the increased female prevalence of arthritic patients (12–14). While there were more female participants, there was no statistical difference in the measured radiographic features between women and men ( P > 0.05).…”

Manually and automatically produced pellet cultures of human primary chondrocytes: A comparative analysis

“…investigated shape and size of manually produced pellet cultures in tubes and well plates. They detected an increased spherical over time and consistent roundness of the pellets cultures . We support these observations.…”

Post-Arthroplasty Spatiotemporal Gait Parameters in Patients with Hip Osteoarthritis or Developmental Dysplasia of the Hip: An Observational Study

“…On the other hand, DDH is the most common cause of secondary osteoarthritis in adults under 40 years of age, since abnormal hip biomechanics resulting in contact stresses predispose patients with DDH to arthritic changes earlier than the normal population and require THA at an early age [37]. Also expected was the fact that our groups consisted of more women than men, in line with studies reporting that hip OA prevalence is higher among women [38], while DDH is more common among girls [37]. Regarding age and sex, our groups were relatively representative of both populations studied [35][36][37][38].…”

“…Also expected was the fact that our groups consisted of more women than men, in line with studies reporting that hip OA prevalence is higher among women [ 38 ], while DDH is more common among girls [ 37 ]. Regarding age and sex, our groups were relatively representative of both populations studied [ 35 , 36 , 37 , 38 ].…”

Osteoarthritis of the hip: are degenerative tears of the acetabular labrum predictable from features on hip radiographs?

“…The demographic data of the present study demonstrates a female subject predominance, a finding that parallels the existing literature showing the increased female prevalence of arthritic patients (12–14). While there were more female participants, there was no statistical difference in the measured radiographic features between women and men ( P > 0.05).…”

Manually and automatically produced pellet cultures of human primary chondrocytes: A comparative analysis

“…investigated shape and size of manually produced pellet cultures in tubes and well plates. They detected an increased spherical over time and consistent roundness of the pellets cultures . We support these observations.…”

Post-Arthroplasty Spatiotemporal Gait Parameters in Patients with Hip Osteoarthritis or Developmental Dysplasia of the Hip: An Observational Study

“…On the other hand, DDH is the most common cause of secondary osteoarthritis in adults under 40 years of age, since abnormal hip biomechanics resulting in contact stresses predispose patients with DDH to arthritic changes earlier than the normal population and require THA at an early age [37]. Also expected was the fact that our groups consisted of more women than men, in line with studies reporting that hip OA prevalence is higher among women [38], while DDH is more common among girls [37]. Regarding age and sex, our groups were relatively representative of both populations studied [35][36][37][38].…”

“…Also expected was the fact that our groups consisted of more women than men, in line with studies reporting that hip OA prevalence is higher among women [ 38 ], while DDH is more common among girls [ 37 ]. Regarding age and sex, our groups were relatively representative of both populations studied [ 35 , 36 , 37 , 38 ].…”

Osteoarthritis of the hip: are degenerative tears of the acetabular labrum predictable from features on hip radiographs?

“…The demographic data of the present study demonstrates a female subject predominance, a finding that parallels the existing literature showing the increased female prevalence of arthritic patients (12–14). While there were more female participants, there was no statistical difference in the measured radiographic features between women and men ( P > 0.05).…”

Manually and automatically produced pellet cultures of human primary chondrocytes: A comparative analysis

“…investigated shape and size of manually produced pellet cultures in tubes and well plates. They detected an increased spherical over time and consistent roundness of the pellets cultures . We support these observations.…”

Post-Arthroplasty Spatiotemporal Gait Parameters in Patients with Hip Osteoarthritis or Developmental Dysplasia of the Hip: An Observational Study

“…On the other hand, DDH is the most common cause of secondary osteoarthritis in adults under 40 years of age, since abnormal hip biomechanics resulting in contact stresses predispose patients with DDH to arthritic changes earlier than the normal population and require THA at an early age [37]. Also expected was the fact that our groups consisted of more women than men, in line with studies reporting that hip OA prevalence is higher among women [38], while DDH is more common among girls [37]. Regarding age and sex, our groups were relatively representative of both populations studied [35][36][37][38].…”

“…Also expected was the fact that our groups consisted of more women than men, in line with studies reporting that hip OA prevalence is higher among women [ 38 ], while DDH is more common among girls [ 37 ]. Regarding age and sex, our groups were relatively representative of both populations studied [ 35 , 36 , 37 , 38 ].…”