Challenges in SERS-based pesticide detection and plausible solutions

Bernat, Andrea; Samiwala, Mustafa; Albo, Jonathan; Jiang, Xingyi; Rao, Qinchun

doi:10.1021/acs.jafc.9b05077

Cited by 72 publications

(25 citation statements)

References 73 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It makes it harder for each analyte to be detected specifically. 149 Significantly, this can be extended to the healthcare applications of SERS in the disease's regime for the pathogen, bacterial, and viruses' diagnostics. Moreover, this can be termed as a significant disadvantage of SERS in terms of the recent use of this technique in the medical field.…”

Section: Commercial Kits For Detection Of Sars-cov-2mentioning

confidence: 99%

“…This could be easily extended in terms of clinical samples and diagnosis of analytes at extremely lower concentrations. It makes it harder for each analyte to be detected specifically . Significantly, this can be extended to the healthcare applications of SERS in the disease’s regime for the pathogen, bacterial, and viruses’ diagnostics.…”

Section: Challenges Associated With Sers-based Covid-19 Diagnostics M...mentioning

confidence: 99%

See 1 more Smart Citation

SERS Based Lateral Flow Immunoassay for Point-of-Care Detection of SARS-CoV-2 in Clinical Samples

Yadav

Sadique

Ranjan

et al. 2021

ACS Appl. Bio Mater.

143

119

View full text Add to dashboard Cite

The current scenario, an ongoing pandemic of COVID-19, places a dreadful burden on the healthcare system worldwide. Subsequently, there is a need for a rapid, user-friendly, and inexpensive on-site monitoring system for diagnosis. The early and rapid diagnosis of SARS-CoV-2 plays an important role in combating the outbreak. Although conventional methods such as PCR, RT-PCR, and ELISA, etc., offer a gold-standard solution to manage the pandemic, they cannot be implemented as a point-of-care (POC) testing arrangement. Moreover, surface-enhanced Raman spectroscopy (SERS) having a high enhancement factor provides quantitative results with high specificity, sensitivity, and multiplex detection ability but lacks in POC setup. In contrast, POC devices such as lateral flow immunoassay (LFIA) offer rapid, simple-to-use, cost-effective, reliable platform. However, LFIA has limitations in quantitative and sensitive analyses of SARS-CoV-2 detection. To resolve these concerns, herein we discuss a unique modality that is an integration of SERS with LFIA for quantitative analyses of SARS-CoV-2. The miniaturization ability of SERS-based devices makes them promising in biosensor application and has the potential to make a better alternative of conventional diagnostic methods. This review also demonstrates the commercially available and FDA/ICMR approved LFIA kits for on-site diagnosis of SARS-CoV-2.

show abstract

Section: Commercial Kits For Detection Of Sars-cov-2mentioning

confidence: 99%

Section: Challenges Associated With Sers-based Covid-19 Diagnostics M...mentioning

confidence: 99%

SERS Based Lateral Flow Immunoassay for Point-of-Care Detection of SARS-CoV-2 in Clinical Samples

Yadav

Sadique

Ranjan

et al. 2021

ACS Appl. Bio Mater.

143

119

View full text Add to dashboard Cite

show abstract

“…However, metal nanoparticles immobilized on some platforms are usually functionalized with amino or thiol groups. Others methods for nanoparticles grown on the solid substrate include capillary force, electrostatic interactions or electron beam lithography [130]. The disadvantage of these methods is relatively costly and limits its application in food safety.…”

Section: How To Choose Suitable Substrate For Sers Detection Of Pesticidesmentioning

confidence: 99%

“…Another reason for influencing selectivity is the false positives of nonspecific binding, which may include hydrophobic interaction, hydrogen bond, Van der Waals' force, and electrostatic force [137]. To reduce these problems, some chemicals can modify and help particles avoid these false results, such as bovine serum albumin and polyethylene glycol [130]. Despite some pretreatment method can partly solve this problem, the simpler and time-saving method should be explored in the future.…”

Section: How To Choose Suitable Substrate For Sers Detection Of Pesticidesmentioning

confidence: 99%

Rapid field trace detection of pesticide residue in food based on surface-enhanced Raman spectroscopy

Liang

Wen-wen

et al. 2021

Microchim Acta

View full text Add to dashboard Cite

Surface-enhanced Raman spectroscopy is an alternative detection tool for monitoring food security. However, there is still a lack of a conclusion of SERS detection with respect to pesticides and real sample analysis, and the summary of intelligent algorithms in SERS is also a blank. In this review, a comprehensive report of pesticides detection using SERS technology is given. The SERS detection characteristics of different types of pesticides and the influence of substrate on inspection are discussed and compared by the typical ways of classification. The key points, including the progress in real sample analysis and Raman data processing methods with intelligent algorithm, are highlighted. Lastly, major challenges and future research trends of SERS analysis of pesticide residue are also addressed. SERS has been proven to be a powerful technique for rapid test of residue pesticides in complex food matrices, but there still is a tremendous development space for future research.

show abstract

“…The transducers convert recognition element–target binding events into a measurable signal readout based on changes in fluorescence, ultraviolet, surface-enhanced Raman scattering (SERS), electrochemical output, etc. Among the various transducer techniques, SERS has gained more and more attention in recent decades. − SERS is fingerprint spectroscopy with high selectivity, enabling it to realize the highly sensitive analysis of targets based on a SERS-enhanced substrate, such as gold (Au) or silver (Ag) nanostructures. SERS employed for a transducer has some unique advantages. − The limit of detection (LOD) of SERS-based biosensors can reach a high sensitivity for trace analysis based on the significant enhancement factor up to ∼10 .…”

Section: Introductionmentioning

confidence: 99%

Advances in Surface-Enhanced Raman Scattering-Based Aptasensors for Food Safety Detection

Yan

et al. 2021

J. Agric. Food Chem.

View full text Add to dashboard Cite

Owing to the excellent performances of high sensitivity, high specificity, on-site detection, and multiplexing capability, surface-enhanced Raman scattering (SERS)-based aptasensors have performed prosperous applications and gained impressive progress in food safety. Herein, we reviewed the SERS-based aptasensors from the principles to specific applications in food safety. First, the sensor-working principles, SERS label design and preparation are introduced. Then, the popular platforms in the aptasensors are summarized with their advantages and disadvantages, followed by their representative applications. Further, the specific applications of developing SERS-based aptasensors in food safety are systematically provided. Moreover, the multiplex analysis using SERS labels are highlighted. Finally, challenges and perspectives for improving the SERS-based aptasensor performance are also discussed, aiming to give some proposes for researchers to choose suitable SERS-based aptasensors according to specific applications.

show abstract

Challenges in SERS-based pesticide detection and plausible solutions

Cited by 72 publications

References 73 publications

SERS Based Lateral Flow Immunoassay for Point-of-Care Detection of SARS-CoV-2 in Clinical Samples

SERS Based Lateral Flow Immunoassay for Point-of-Care Detection of SARS-CoV-2 in Clinical Samples

Rapid field trace detection of pesticide residue in food based on surface-enhanced Raman spectroscopy

Advances in Surface-Enhanced Raman Scattering-Based Aptasensors for Food Safety Detection

Contact Info

Product

Resources

About