Challenges in SERS-based pesticide detection and plausible solutions

Colloidal dendritic nanostructures of gold and silver for SERS analysis of water pollutants

“…These include a high number of open nanojunctions due to the presence of clustered metal nanoparticles, coupling of localized surface plasmons of Au:Ag nanostructures resulting in the enhancement of the localized electromagnetic field and, as previously reported by our group, the dendrimer also favours the entrapment of target molecules close to the metal surfaces promoting better SERS signal sensitivity and homogeneity (Supporting information, Figure S11) [2,44,[62][63][64][65]. Also, the PAMAM dendrimer has a key role in the in-situ formation of these structures by providing long-term colloidal stability, which is a crucial parameter for practical applications of metal colloids in SERS detection of water pollutants.…”

Colloidal dendritic nanostructures of gold and silver for SERS analysis of water pollutants

“…These include a high number of open nanojunctions due to the presence of clustered metal nanoparticles, coupling of localized surface plasmons of Au:Ag nanostructures resulting in the enhancement of the localized electromagnetic field and, as previously reported by our group, the dendrimer also favours the entrapment of target molecules close to the metal surfaces promoting better SERS signal sensitivity and homogeneity (Supporting information, Figure S11) [2,44,[62][63][64][65]. Also, the PAMAM dendrimer has a key role in the in-situ formation of these structures by providing long-term colloidal stability, which is a crucial parameter for practical applications of metal colloids in SERS detection of water pollutants.…”

Advances in Optical Biosensors for Pesticide Detection

“…These substrates enhance molecular vibrations, enabling highly sensitive and specific detection. In pesticide analysis, SERS has shown greatly improved sensitivity and is evolving from simple signal enhancement toward intelligent, automated analysis [ 75 ]. This progress is driven by 2 key approaches: integrating biorecognition elements and designing multi-dimensional metallic substrates.…”

SERS Based Lateral Flow Immunoassay for Point-of-Care Detection of SARS-CoV-2 in Clinical Samples

“…It makes it harder for each analyte to be detected specifically. 149 Significantly, this can be extended to the healthcare applications of SERS in the disease's regime for the pathogen, bacterial, and viruses' diagnostics. Moreover, this can be termed as a significant disadvantage of SERS in terms of the recent use of this technique in the medical field.…”

Colloidal dendritic nanostructures of gold and silver for SERS analysis of water pollutants

“…These include a high number of open nanojunctions due to the presence of clustered metal nanoparticles, coupling of localized surface plasmons of Au:Ag nanostructures resulting in the enhancement of the localized electromagnetic field and, as previously reported by our group, the dendrimer also favours the entrapment of target molecules close to the metal surfaces promoting better SERS signal sensitivity and homogeneity (Supporting information, Figure S11) [2,44,[62][63][64][65]. Also, the PAMAM dendrimer has a key role in the in-situ formation of these structures by providing long-term colloidal stability, which is a crucial parameter for practical applications of metal colloids in SERS detection of water pollutants.…”

Advances in Optical Biosensors for Pesticide Detection

“…These substrates enhance molecular vibrations, enabling highly sensitive and specific detection. In pesticide analysis, SERS has shown greatly improved sensitivity and is evolving from simple signal enhancement toward intelligent, automated analysis [ 75 ]. This progress is driven by 2 key approaches: integrating biorecognition elements and designing multi-dimensional metallic substrates.…”

SERS Based Lateral Flow Immunoassay for Point-of-Care Detection of SARS-CoV-2 in Clinical Samples

“…It makes it harder for each analyte to be detected specifically. 149 Significantly, this can be extended to the healthcare applications of SERS in the disease's regime for the pathogen, bacterial, and viruses' diagnostics. Moreover, this can be termed as a significant disadvantage of SERS in terms of the recent use of this technique in the medical field.…”

Colloidal dendritic nanostructures of gold and silver for SERS analysis of water pollutants

“…These include a high number of open nanojunctions due to the presence of clustered metal nanoparticles, coupling of localized surface plasmons of Au:Ag nanostructures resulting in the enhancement of the localized electromagnetic field and, as previously reported by our group, the dendrimer also favours the entrapment of target molecules close to the metal surfaces promoting better SERS signal sensitivity and homogeneity (Supporting information, Figure S11) [2,44,[62][63][64][65]. Also, the PAMAM dendrimer has a key role in the in-situ formation of these structures by providing long-term colloidal stability, which is a crucial parameter for practical applications of metal colloids in SERS detection of water pollutants.…”

Advances in Optical Biosensors for Pesticide Detection

“…These substrates enhance molecular vibrations, enabling highly sensitive and specific detection. In pesticide analysis, SERS has shown greatly improved sensitivity and is evolving from simple signal enhancement toward intelligent, automated analysis [ 75 ]. This progress is driven by 2 key approaches: integrating biorecognition elements and designing multi-dimensional metallic substrates.…”

SERS Based Lateral Flow Immunoassay for Point-of-Care Detection of SARS-CoV-2 in Clinical Samples

“…It makes it harder for each analyte to be detected specifically. 149 Significantly, this can be extended to the healthcare applications of SERS in the disease's regime for the pathogen, bacterial, and viruses' diagnostics. Moreover, this can be termed as a significant disadvantage of SERS in terms of the recent use of this technique in the medical field.…”