Adherence to the Mediterranean Diet Is Associated with Better Metabolic Features in Youths with Type 1 Diabetes

Antoniotti, Valentina; Spadaccini, Daniele; Ricotti, Roberta; Carrera, Deborah; Savastio, Silvia; Correia, Filipa; Caputo, Marina; Pozzi, Erica; Bellone, Simonetta; Rabbone, Ivana; Prodam, Flavia

doi:10.3390/nu14030596

Cited by 20 publications

(23 citation statements)

References 78 publications

(88 reference statements)

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“…KIDMED scores displayed average values in 58.6% of the subjects, in line with data from a non-diabetic population of Italians of the same age range [8]. Low adherence to the MD was associated with a high risk of obesity in T1D, as reported in the general pediatric and adult population [17]. Regarding the prospective relation between diet pattern and total cancer risk, Yiannakou et al [18] examined in a prospective study the longitudinal association between the Mediterraneanstyle dietary pattern (MSDP) score, derived from a semi-quantitative food frequency questionnaire, and total cancer risk in 2966 participants of the Framingham Offspring Study cohort, displaying weaker association between MSDP score and cancer risk in men except in non-smokers, while higher adherence to MSDP was associated with lower cancer risk, especially among women [18], confirming that the MD as a source of bioactive compounds protects against cancer [19].…”

supporting

confidence: 85%

“…Apart from the studies evaluating adherence to the MD in different contexts, also interesting was the relationship between diet and some metabolic and chronic diseases, such as type 1 diabetes (T1D) and cancer. In this scenario, Antoniotti et al [17] assessed the MD adherence by the Mediterranean Diet Quality Index (KIDMED) questionnaire in 65 children and adolescents with T1D in relation to metabolic control. KIDMED scores displayed average values in 58.6% of the subjects, in line with data from a non-diabetic population of Italians of the same age range [8].…”

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confidence: 99%

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Mediterranean Diet and Physical Activity as Healthy Lifestyles for Human Health

Bonofiglio

2022

Nutrients

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supporting

confidence: 85%

mentioning

confidence: 99%

Mediterranean Diet and Physical Activity as Healthy Lifestyles for Human Health

Bonofiglio

2022

Nutrients

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“…Two cross‐sectional studies 14,15 also found an association between adherence to the Mediterranean diet and better glycaemic control in children and adolescents with T1D. Another study conducted in youth with T1D 16 showed the benefit of a number of dietary habits typical of the Mediterranean diet (consumption of dairy products at breakfast, extra virgin olive oil or fish) with lower HbA1c and blood pressure.…”

Section: Discussionmentioning

confidence: 96%

“…In primary and secondary prevention RCTs, increased adherence to the Mediterranean dietary pattern has been shown to significantly reduce major cardiovascular events 11–13 . In people with T1D, greater adherence to the Mediterranean diet has been associated with improved glycaemic control 14,15 and various metabolic parameters 16 . However, little information is available on the relationship of the Mediterranean diet with atherosclerosis and CVD 17,18 .…”

Section: Introductionmentioning

confidence: 99%

Adherence to an energy‐restricted Mediterranean diet is associated with the presence and burden of carotid atherosclerosis in people with type 1 diabetes

Serés‐Noriega,

Viñals,

Perea

et al. 2024

Diabetes Metabolism Res

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AimsPeople with type 1 diabetes (T1D) have an increased risk of cardiovascular disease (CVD). The Mediterranean diet is associated with reduced CVD; however, the evidence in T1D is scarce. We aimed to analyse the relationships between adherence to the energy‐restricted Mediterranean diet (erMEDd) and carotid atherosclerosis.Materials and MethodsWe included children with T1D without CVD, with ≥1 of the following: age ≥40 years, diabetic kidney disease, or ≥10 years of disease duration with another risk factor. Plaque presence (intima‐media thickness ≥1.5 mm) was determined by ultrasonography. The PREDIMED‐Plus 17‐item questionnaire (PP‐17) was used to assess adherence to the erMEDd.ResultsFour hundred one individuals were included (48% males, age 48.3 ± 11 years, diabetes duration 26.8 ± 11.4 years). Those harbouring plaques (42%) showed lower adherence to the erMEDd (PP‐17: 8.9 ± 2.3 of a maximum of 17 vs. 9.8 ± 2.5, p < 0.001). Greater adherence to the erMEDd was correlated with an overall better metabolic profile. After adjusting for multiple confounders, adherence to the erMEDd was independently associated with carotid atherosclerosis (OR 0.86 [0.77–0.95] for plaque presence and OR 0.85 [0.75–0.97] for ≥2 plaques). The consumption of fruit and nuts and preference of white over red meat was higher in individuals without atherosclerosis (p < 0.05). Fruit and nut consumption was associated with lower plaque prevalence in the fully adjusted models (OR 0.38 [0.19–0.73] and 0.51 [0.29–0.93]).ConclusionsGreater adherence to the erMEDd is associated with less carotid atherosclerosis in children with T1D at high risk of CVD. Strategies to improve and implement healthy dietary patterns in this population should be encouraged.

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“…Persons on medications to lower blood cholesterol should monitor their cholesterol levels. Various cautions are indicated [49] . Skin: Fruit and leaves are used in leprosy.…”

Section: Isolation Of Charantinmentioning

confidence: 99%

Role of Karela in Diabetes: A Review

Sharma¹,

Kumar

2023

J. Res. Appl. Sci. Biotechnol.

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Diabetes mellitus is among the most common disorder in developed and developing countries, and the disease is increasing rapidly in most parts of the world. It has been estimated that up to one-third of patients with diabetes mellitus use some form of complementary and alternative medicine. One plant that has received the most attention for its anti-diabetic properties is bitter melon, Momordica charantia (M. charantia), commonly referred to as bitter gourd, karela and balsam pear. Its fruit is also used for the treatment of diabetes and related conditions amongst the indigenous populations of Asia, South America, India and East Africa. Abundant pre-clinical studies have documented in the anti-diabetic and hypoglycaemic effects of M. charantia through various postulated mechanisms. However, clinical trial data with human subjects are limited and flawed by poor study design and low statistical power. The present review is an attempt to highlight the antidiabetic activity as well as phytochemical and pharmacological reports on M. charantia and calls for better-designed clinical trials to further elucidate its possible therapeutic effects on diabetes.

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Adherence to the Mediterranean Diet Is Associated with Better Metabolic Features in Youths with Type 1 Diabetes

Cited by 20 publications

References 78 publications

Mediterranean Diet and Physical Activity as Healthy Lifestyles for Human Health

Mediterranean Diet and Physical Activity as Healthy Lifestyles for Human Health

Adherence to an energy‐restricted Mediterranean diet is associated with the presence and burden of carotid atherosclerosis in people with type 1 diabetes

Role of Karela in Diabetes: A Review

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